Glaucoma is an irreversible progressive optic neuropathy, for which the major proven
treatment is to lower the intraocular pressure (IOP). Five groups of IOP‐lowering eye drops …

Neuroimmune communication plays a crucial role in maintaining homeostasis and promptly
responding to any foreign insults. Sympathetic nerve fibres are innervated into all the …

Abstract Development of ocular drug delivery system is one of the most technically
challenging tasks, when compared with other routes of drug delivery. Eye (an intricate …

Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

Carbonic anhydrase inhibitors (CAIs) have been used for many decades in the treatment of
glaucoma. Systemic CAIs were an early treatment option to lower intraocular pressure by …

Ocular surface disease (OSD), a disorder affecting the lacrimal and meibomian glands and
the corneal and conjunctival epithelium, is a well-known complication of topical glaucoma …

Introduction Glaucoma, a neuropathy characterized by increased intraocular pressure (IOP),
is the major cause of blindness worldwide and its treatment aims at reducing IOP. Areas …

Topical anti-glaucomatous medications are still the most important measure to lower
intraocular pressure. Large number of studies have confirmed that long-term use of anti …

It has been known for some time that Carbonic Anhydrase (CA, EC 4.2. 1.1) plays a complex
role in vascular function, and in the regulation of vascular tone. Clinically employed CA …

Glaucoma [1-8] and macular degeneration [9-11] are among the ophthalmologic diseases
increasingly affecting the aging population worldwide. It is estimated that around 76 million …