The immunologic role of IL-17 in psoriasis and psoriatic arthritis pathogenesis

A Blauvelt, A Chiricozzi - Clinical reviews in allergy & immunology, 2018 - Springer
Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven
by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17 …

Management of psoriasis as a systemic disease: what is the evidence?

NJ Korman - British Journal of Dermatology, 2020 - academic.oup.com
Background Psoriasis is a chronic, systemic immune‐mediated disease characterized by
development of erythematous, indurated, scaly, pruritic and often painful skin plaques …

Macrophage phenotype and function in different stages of atherosclerosis

I Tabas, KE Bornfeldt - Circulation research, 2016 - Am Heart Assoc
The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences

WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

Interleukin-17 and innate immunity in infections and chronic inflammation

N Isailovic, K Daigo, A Mantovani, C Selmi - Journal of autoimmunity, 2015 - Elsevier
Abstract Interleukin 17 (IL-17) includes several cytokines among which IL-17A is considered
as one of the major pro-inflammatory cytokine being central to the innate and adaptive …

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

KPA MacDonald, GR Hill… - Blood, The Journal of the …, 2017 - ashpublications.org
With the increasing use of mismatched, unrelated, and granulocyte colony-stimulating factor–
mobilized peripheral blood stem cell donor grafts and successful treatment of older …

IL-17A in psoriasis and beyond: cardiovascular and metabolic implications

E von Stebut, WH Boehncke, K Ghoreschi… - Frontiers in …, 2020 - frontiersin.org
Interleukin 17A (IL-17A) is one of the currently known six members of the IL-17 cytokine
family and is implicated in immune responses to infectious pathogens and in the …

Cytokine circuits in cardiovascular disease

JW Williams, L Huang, GJ Randolph - Immunity, 2019 - cell.com
Arterial inflammation is a hallmark of atherosclerosis, and appropriate management of this
inflammation represents a major unmet therapeutic need for cardiovascular disease …

Atherosclerosis and immunity: a perspective

F Abdolmaleki, SMG Hayat, V Bianconi… - Trends in cardiovascular …, 2019 - Elsevier
Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …