Type 2 diabetes mellitus in youth exposed to antipsychotics: a systematic review and meta-analysis

B Galling, A Roldan, RE Nielsen, J Nielsen… - JAMA …, 2016 - jamanetwork.com
Importance Antipsychotics are used increasingly in youth for nonpsychotic and off-label
indications, but cardiometabolic adverse effects and (especially) type 2 diabetes mellitus …

Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: a systematic review of randomized, placebo controlled …

M De Hert, M Dobbelaere, EM Sheridan… - European …, 2011 - cambridge.org
Second-generation antipsychotics (SGA) are being used more often than ever before in
children and adolescents with psychotic and a wide range of non-psychotic disorders …

Antipsychotics and the risk of type 2 diabetes mellitus in children and youth

WV Bobo, WO Cooper, CM Stein, M Olfson… - JAMA …, 2013 - jamanetwork.com
Importance The increased prescribing of antipsychotics for children and youth has
heightened concerns that this practice increases the risk of type 2 diabetes mellitus …

Evidence-based recommendations for monitoring safety of second-generation antipsychotics in children and youth

T Pringsheim, C Panagiotopoulos… - Paediatrics & child …, 2011 - academic.oup.com
BACKGROUND: The use of antipsychotics, especially second-generation antipsychotics
(SGAs), for children with mental health disorders in Canada has increased dramatically over …

Metabolic syndrome with the atypical antipsychotics

P Pramyothin, L Khaodhiar - Current Opinion in Endocrinology …, 2010 - journals.lww.com
Metabolic syndrome with the atypical antipsychotics : Current Opinion in Endocrinology,
Diabetes and Obesity Metabolic syndrome with the atypical antipsychotics : Current Opinion in …

Pediatric obesity epidemiology

CM Orsi, DE Hale, JL Lynch - Current Opinion in endocrinology …, 2011 - journals.lww.com
The health and financial consequences of this epidemic are a complex global public health
dilemma. International efforts are underway to reverse these obesity trends. On-going …

Second-generation antipsychotic use in children and adolescents: a six-month prospective cohort study in drug-naïve patients

C Arango, M Giráldez, J Merchán-Naranjo… - Journal of the American …, 2014 - Elsevier
Objective To assess weight and metabolic effects of 6 months of treatment with second-
generation antipsychotics in naïve/quasi-naïve youths. Method This study looked at a …

A population-based study of antipsychotic prescription trends in children and adolescents in British Columbia, from 1996 to 2011

R Ronsley, D Scott, WP Warburton… - The Canadian …, 2013 - journals.sagepub.com
Objectives: To establish prevalence rates of antipsychotic (AP) prescriptions for children 18
years of age or younger in British Columbia (BC) from 1996 to 2011 by age, sex, AP type …

Corrected QT changes during antipsychotic treatment of children and adolescents: a systematic review and meta-analysis of clinical trials

KG Jensen, K Juul, A Fink-Jensen, CU Correll… - Journal of the American …, 2015 - Elsevier
Objective To evaluate the effect of antipsychotics on the corrected QT (QTc) interval in youth.
Method We searched PubMed (http://www. ncbi. nlm. nih. gov/pubmed) for randomized or …

Risperidone-induced weight gain and reduced locomotor activity in juvenile female rats: the role of histaminergic and NPY pathways

J Lian, M De Santis, M He, C Deng - Pharmacological research, 2015 - Elsevier
Second generation antipsychotic drugs (SGAs) such as risperidone are increasingly
prescribed (mostly for off-label use) to children and adolescents for treating various mental …