Grape pomace polyphenols improve insulin response to a standard meal in healthy individuals: A pilot study

G Costabile, M Vitale, D Luongo, D Naviglio, C Vetrani… - Clinical nutrition, 2019 - Elsevier
Background & aims Dietary polyphenols have beneficial effects on glucose/lipid metabolism
in subjects at high risk to develop type 2 diabetes; however, the underlying mechanisms are …

AMPK as a new attractive therapeutic target for disease prevention: the role of dietary compounds AMPK and disease prevention

M Gasparrini, F Giampieri… - Current drug …, 2016 - ingentaconnect.com
AMPK is a serine/threonine protein kinase that has the function of maintaining the balance
between ATP production and consumption in most eukaryotic cells. It plays a relevant role in …

Structurally different flavonoid subclasses attenuate high-fat and high-fructose diet induced metabolic syndrome in rats

J Zhang, L Zhao, Q Cheng, B Ji, M Yang… - Journal of agricultural …, 2018 - ACS Publications
Metabolic syndrome is a serious health problem worldwide. Increasing evidence indicates
that flavonoid-rich foods exert beneficial effects. However, the function of flavonoids in …

[PDF][PDF] Encapsulation systems for delivery of flavonoids: A

M Yousefi, M Shadnoush… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Encapsulation of bioactive compounds s been considered a promising tool for preserving
these compounds. Several studies on dietary sources and health benefits of flavonoids, their …

A comprehensive review on the antidiabetic activity of flavonoids targeting PTP1B and DPP-4: A structure-activity relationship analysis

C Proença, D Ribeiro, M Freitas… - Critical reviews in …, 2022 - Taylor & Francis
Abstract Type 2 diabetes (T2D) is an expanding global health problem, resulting from
defects in insulin secretion and/or insulin resistance. In the past few years, both protein …

[HTML][HTML] Hypoglycemic, antidyslipidemic and antioxydant effects of Vitellaria paradoxa barks extract on high-fat diet and streptozotocin-induced type 2 diabetes rats

D Miaffo, F Ntchapda, TA Mahamad, B Maidadi… - Metabolism Open, 2021 - Elsevier
Backgroud Vitellaria paradoxa is a plant belonging to the Sapotaceae family and used in
traditional medicine in the treatment of diabetes mellitus. The aim of this work was to …

Antioxidant capacities of flavones and benefits in oxidative-stress related diseases

MD Catarino, JM Alves-Silva… - Current Topics in …, 2015 - ingentaconnect.com
Flavonoids, a group of secondary metabolites widely distributed in the plant kingdom, have
been acknowledged for their interesting medicinal properties. Among them, natural flavones …

Didymin, a dietary citrus flavonoid exhibits anti-diabetic complications and promotes glucose uptake through the activation of PI3K/Akt signaling pathway in insulin …

MY Ali, S Zaib, MM Rahman, S Jannat, J Iqbal… - Chemico-Biological …, 2019 - Elsevier
Didymin is a naturally occurring orally active flavonoid glycoside (isosakuranetin 7-O-
rutinoside) found in various citrus fruits, which has been previously reported to possess a …

Number of hydroxyl groups on the B-ring of flavonoids affects their antioxidant activity and interaction with phorbol ester binding site of PKCδ C1B domain: in vitro and …

T Kongpichitchoke, JL Hsu… - Journal of agricultural and …, 2015 - ACS Publications
Although flavonoids have been reported for their benefits and nutraceutical potential use,
the importance of their structure on their beneficial effects, especially on signal transduction …

[HTML][HTML] Gut microbiome and chronic prostatitis/chronic pelvic pain syndrome

HC Arora, C Eng, DA Shoskes - Annals of translational medicine, 2017 - ncbi.nlm.nih.gov
Abstract Analysis of the human microbiome continues to reveal new and previously
unrealized associations between microbial dysbiosis and disease. Novel approaches to …