The majority of research on the long-term effects of spinal cord injury (SCI) has primarily
focused on neuropathic pain (NP), psychological issues, and sensorimotor impairments …

Modulating the immune system to treat diseases, including myeloid malignancies, has
resulted in the development of a multitude of novel therapeutics in recent years …

Inflammasomes are important modulators of inflammation. Dysregulation of inflammasomes
can enhance vulnerability to conditions such as neurodegenerative diseases …

Previous studies have demonstrated a bidirectional relationship between inflammation and
depression. Activation of the nucleotide-binding oligomerization domain, leucine-rich repeat …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease of undefined etiology,
with persistent synovial inflammation and destruction of articular cartilage and bone. Current …

Parkinson's disease (PD) is a neurodegenerative disease for which the prevalence is
second only to Alzheimer's disease (AD). This disease primarily affects people of middle and …

Social isolation stress (SIS) is associated with affective disorders (ie, anxiety and
depression) in adults. In a preclinical study, we aimed to investigate the effects of resveratrol …

Atherosclerosis (AS) is the primary pathology behind various cardiovascular diseases and
the leading cause of death and disability globally. Recent evidence suggests that AS is a …

Background The involvement of NLRP3 inflammasome is associated with the progress of
numerous inflammatory conditions. However, there is currently no single compound used in …

Epilepsy is one of the most prevalent and serious brain disorders and affects over 70 million
people globally. Antiseizure medications (ASMs) relieve symptoms and prevent the …