The expansion of human T-bethighCD21low B cells is T cell dependent
B Keller, V Strohmeier, I Harder, S Unger… - Science …, 2021 - science.org
Accumulation of human CD21low B cells in peripheral blood is a hallmark of chronic
activation of the adaptive immune system in certain infections and autoimmune disorders …
activation of the adaptive immune system in certain infections and autoimmune disorders …
[HTML][HTML] Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases
H Hao, S Nakayamada, Y Tanaka - Inflammation and Regeneration, 2021 - Springer
T follicular helper cells participate in stimulating germinal center (GC) formation and
supporting B cell differentiation and autoantibody production. However, T follicular …
supporting B cell differentiation and autoantibody production. However, T follicular …
[HTML][HTML] Functions of Tfh Cells in Common Variable Immunodeficiency
C Le Saos-Patrinos, S Loizon, P Blanco… - Frontiers in …, 2020 - frontiersin.org
Common variable immunodeficiency is the most common clinical primary immunodeficiency
in adults. Its hallmarks are hypogammaglobulinemia and compromised B-cell differentiation …
in adults. Its hallmarks are hypogammaglobulinemia and compromised B-cell differentiation …
[HTML][HTML] A landscape of gene expression regulation for synovium in arthritis
F Jiang, SY Hu, W Tian, NN Wang, N Yang… - Nature …, 2024 - nature.com
The synovium is an important component of any synovial joint and is the major target tissue
of inflammatory arthritis. However, the multi-omics landscape of synovium required for …
of inflammatory arthritis. However, the multi-omics landscape of synovium required for …
[HTML][HTML] COVID-19 vaccination responses with different vaccine platforms in patients with inborn errors of immunity
L Erra, I Uriarte, A Colado, MV Paolini… - Journal of Clinical …, 2023 - Springer
Patients with inborn errors of immunity (IEI) in Argentina were encouraged to receive
licensed Sputnik, AstraZeneca, Sinopharm, Moderna, and Pfizer vaccines, even though …
licensed Sputnik, AstraZeneca, Sinopharm, Moderna, and Pfizer vaccines, even though …
[HTML][HTML] UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE
L Liu, L Hu, L Yang, S Jia, P Du, X Min, J Wu, H Wu… - Clinical …, 2021 - Springer
Background Transcription factor B cell lymphoma 6 (BCL6) is a master regulator of T
follicular helper (Tfh) cells, which play a crucial role in the pathogenesis of systemic lupus …
follicular helper (Tfh) cells, which play a crucial role in the pathogenesis of systemic lupus …
Allergen immunotherapy enhances the immunosuppressive effects of Treg cells to alleviate allergic rhinitis by decreasing PU-1+ Treg cell numbers
YL Qiao, WE Jiao, S Xu, YG Kong, YQ Deng… - International …, 2022 - Elsevier
Objective To investigate the role of Tregs and their subtypes in the treatment of allergic
rhinitis with allergen immunotherapy (AIT) as well as the underlying mechanism. Methods 1 …
rhinitis with allergen immunotherapy (AIT) as well as the underlying mechanism. Methods 1 …
[HTML][HTML] Follicular helper T cells in immunity and autoimmunity
MP Cicalese, S Salek-Ardakani, G Fousteri - Frontiers in Immunology, 2020 - frontiersin.org
In the last two decades, a new population of CD4+ helper T cells, named T follicular helper
cells (Tfh), was shown to be specialized in “helping” the germinal center (GC) response and …
cells (Tfh), was shown to be specialized in “helping” the germinal center (GC) response and …
Mistuned NF-κB signaling in lymphocytes: lessons from relevant inborn errors of immunity
G Dabbah-Krancher, AL Snow - Clinical and Experimental …, 2023 - academic.oup.com
Inborn errors of immunity (IEIs) continuously remind us that multiple checks and balances
are built into the adaptive immune system to maintain homeostasis, ensuring effective …
are built into the adaptive immune system to maintain homeostasis, ensuring effective …
[HTML][HTML] Sterilizing Immunity against COVID-19: Developing Helper T cells I and II activating vaccines is imperative
I Kyei-Barffour, SA Addo, E Aninagyei… - Biomedicine & …, 2021 - Elsevier
Six months after the publication of the severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) sequence, a record number of vaccine candidates were listed, and quite a …
(SARS-CoV-2) sequence, a record number of vaccine candidates were listed, and quite a …