Bioactive peptides: From basic research to clinical trials and commercialization
P Duffuler, KS Bhullar… - Journal of agricultural …, 2022 - ACS Publications
Chronic diseases, including metabolic diseases, have become a worldwide public health
issue. Research regarding the use of bioactive peptides or protein hydrolysates derived from …
issue. Research regarding the use of bioactive peptides or protein hydrolysates derived from …
Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges
Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the
rapidly growing elderly population in the developing world. The currently FDA approved …
rapidly growing elderly population in the developing world. The currently FDA approved …
Current trends and perspectives of bioactive peptides
The remarkable growth of therapeutic peptide development in the past decade has led to a
large number of market approvals and the market value is expected to hit $25 billion by …
large number of market approvals and the market value is expected to hit $25 billion by …
[HTML][HTML] Central and peripheral control of food intake
MMI Abdalla - Endocrine regulations, 2017 - sciendo.com
The maintenance of the body weight at a stable level is a major determinant in keeping the
higher animals and mammals survive. The body weight depends on the balance between …
higher animals and mammals survive. The body weight depends on the balance between …
Galanin peptide family regulation of glucose metabolism
P Fang, M Yu, M Shi, P Bo, Z Zhang - Frontiers in Neuroendocrinology, 2020 - Elsevier
Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …
[HTML][HTML] Spexin-based galanin receptor type 2 agonist for comorbid mood disorders and abnormal body weight
Despite the established comorbidity between mood disorders and abnormal eating
behaviors, the underlying molecular mechanism and therapeutics remain to be resolved …
behaviors, the underlying molecular mechanism and therapeutics remain to be resolved …
[HTML][HTML] Neuropeptidergic control of feeding: Focus on the galanin family of peptides
P Marcos, R Coveñas - International Journal of Molecular Sciences, 2021 - mdpi.com
Obesity/overweight are important health problems due to metabolic complications.
Dysregulation of peptides exerting orexigenic/anorexigenic effects must be investigated in …
Dysregulation of peptides exerting orexigenic/anorexigenic effects must be investigated in …
[HTML][HTML] Intranasal delivery of a methyllanthionine-stabilized galanin receptor-2-selective agonist reduces acute food intake
The regulatory (neuro) peptide galanin is widely distributed in the central and peripheral
nervous systems, where it mediates its effects via three G protein-coupled receptors (GAL 1 …
nervous systems, where it mediates its effects via three G protein-coupled receptors (GAL 1 …
[HTML][HTML] Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia
Ischemic stroke-induced neuronal cell death results in the permanent disabling of brain
function. Apoptotic mechanisms are thought to play a prominent role in neuronal injury and …
function. Apoptotic mechanisms are thought to play a prominent role in neuronal injury and …
Pharmacomodulation of brain neuromedin U signaling as a potential therapeutic strategy
A Pałasz, JJ Worthington, Ł Filipczyk… - Journal of …, 2023 - Wiley Online Library
Neuromedin U (NMU) belongs to a family of multifunctional neuropeptides that modulate the
activity of several neural networks of the brain. Acting via metabotropic receptor NMUR2 …
activity of several neural networks of the brain. Acting via metabotropic receptor NMUR2 …