Diagnostic and therapeutic aptamers: a promising pathway to improved cardiovascular disease management
V Di Mauro, FC Lauta, J Modica, SL Appleton… - Basic to Translational …, 2024 - jacc.org
Despite advances in care, cardiovascular diseases remain the leading cause of death
worldwide. As a result, identifying suitable biomarkers for early diagnosis and improving …
worldwide. As a result, identifying suitable biomarkers for early diagnosis and improving …
Precision nanomedicines: Targeting hot mitochondria in cancer cells
R Dou, X Cai, L Ruan, J Zhang, A Rouzi… - ACS Applied Bio …, 2022 - ACS Publications
Mitochondrion is a multifunctional organelle in a cell, and it is one of the important targets of
antitumor therapy. Conventional mitochondrial targeting strategies can hardly distinguish the …
antitumor therapy. Conventional mitochondrial targeting strategies can hardly distinguish the …
Magnetoresponsive functionalized nanocomposite aggregation kinetics and chain formation at the targeted site during magnetic targeting
SI Bernad, V Socoliuc, D Susan-Resiga, I Crăciunescu… - Pharmaceutics, 2022 - mdpi.com
Drug therapy for vascular disease has been promoted to inhibit angiogenesis in
atherosclerotic plaques and prevent restenosis following surgical intervention. This paper …
atherosclerotic plaques and prevent restenosis following surgical intervention. This paper …
Exosome-based WTAP siRNA delivery ameliorates myocardial ischemia-reperfusion injury
T Yin, N Wang, F Jia, Y Wu, L Gao, J Zhang… - European Journal of …, 2024 - Elsevier
Myocardial ischemia/reperfusion (MI/R) injury is the primary cause of postischemic heart
failure. The increased expression of Thioredoxin-interacting protein (TXNIP) has been …
failure. The increased expression of Thioredoxin-interacting protein (TXNIP) has been …
Assessment of circulating extracellular vesicles from calorie‐restricted mice and humans in ischaemic injury models
MSV Jaimes, CT Liao, MM Chen… - Journal of …, 2023 - Wiley Online Library
Calorie restriction (CR) and fasting affect lifespan, disease susceptibility and response to
acute injury across multiple animal models, including ischaemic injuries such as myocardial …
acute injury across multiple animal models, including ischaemic injuries such as myocardial …
Magnetic forces by permanent magnets to manipulate magnetoresponsive particles in drug-targeting applications
SI Bernad, E Bernad - Micromachines, 2022 - mdpi.com
This study presents preliminary computational and experimental findings on two alternative
permanent magnet configurations helpful for magnetic drug administration in vivo. A …
permanent magnet configurations helpful for magnetic drug administration in vivo. A …
Nanoparticles in the new era of cardiovascular therapeutics: challenges and opportunities
P Yang, J Ren, L Yang - International journal of molecular sciences, 2023 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide.
Although a cadre of therapeutic strategies have been made available for CVDs in the clinical …
Although a cadre of therapeutic strategies have been made available for CVDs in the clinical …
Investigation of Cubic and Spherical IONPs' Rheological Characteristics and Aggregation Patterns from the Perspective of Magnetic Targeting
MC Ioncica, S Bandyopadhyay, N Bali, V Socoliuc… - Magnetochemistry, 2023 - mdpi.com
Based on our prior research, we synthesized iron-oxide nanoparticles (IONPs) in two
shapes (spherical and cubic) and sized them for the current inquiry. This research examined …
shapes (spherical and cubic) and sized them for the current inquiry. This research examined …
Review of recent preclinical and clinical research on ligand-targeted liposomes as delivery systems in triple negative breast cancer therapy
M Hajimolaali, FA Dorkoosh… - Journal of Liposome …, 2024 - Taylor & Francis
Triple-negative breast Cancer (TNBC) is one of the deadliest types, making up about 20% of
all breast cancers. Chemotherapy is the traditional manner of progressed TNBC treatment; …
all breast cancers. Chemotherapy is the traditional manner of progressed TNBC treatment; …
[HTML][HTML] Biomimetic nanomaterials in myocardial infarction treatment: Harnessing bionic strategies for advanced therapeutics
T Yu, Q Xu, X Chen, X Deng, N Chen, MT Kou… - Materials Today Bio, 2024 - Elsevier
Myocardial infarction (MI) and its associated poor prognosis pose significant risks to human
health. Nanomaterials hold great potential for the treatment of MI due to their targeted and …
health. Nanomaterials hold great potential for the treatment of MI due to their targeted and …