New insights into the physiopathology of COVID-19: SARS-CoV-2-associated gastrointestinal illness

CA Devaux, JC Lagier, D Raoult - Frontiers in medicine, 2021 - frontiersin.org
Although SARS-CoV-2 is considered a lung-tropic virus that infects the respiratory tract
through binding to the ACE2 cell-surface molecules present on alveolar lungs epithelial …

Age-related changes in intestinal immunity and the microbiome

T Walrath, KU Dyamenahalli… - Journal of Leucocyte …, 2021 - academic.oup.com
The gastrointestinal (GI) tract is a vitally important site for the adsorption of nutrients as well
as the education of immune cells. Homeostasis of the gut is maintained by the interplay of …

Anti-Inflammatory Effects of Lactobacillus Rahmnosus and Bifidobacterium Breve on Cigarette Smoke Activated Human Macrophages

E Mortaz, IM Adcock, FLM Ricciardolo, M Varahram… - PLoS …, 2015 - journals.plos.org
Background Chronic obstructive pulmonary disease (COPD) is a major global health
problem with cigarette smoke (CS) as the main risk factor for its development. Airway …

Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer

J Chau, M Yadav, B Liu, M Furqan, Q Dai, S Shahi… - BMC cancer, 2021 - Springer
Background Though the gut microbiome has been associated with efficacy of
immunotherapy (ICI) in certain cancers, similar findings have not been identified for …

Targeting PI3K-p110α suppresses influenza virus infection in chronic obstructive pulmonary disease

A Chen-Yu Hsu, MR Starkey, I Hanish… - American journal of …, 2015 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) and influenza virus infections are
major global health issues. Patients with COPD are more susceptible to infection, which …

Cross-talk between immune system and microbiota in COVID-19

S Baradaran Ghavami, M Pourhamzeh… - Expert review of …, 2021 - Taylor & Francis
Introduction Human gut microbiota plays a crucial role in providing protective responses
against pathogens, particularly by regulating immune system homeostasis. There is a …

New drug target identification in Vibrio vulnificus by subtractive genome analysis and their inhibitors through molecular docking and molecular dynamics simulations

BS Alotaibi, A Ajmal, MA Hakami, A Mahmood… - Heliyon, 2023 - cell.com
Vibrio vulnificus is a rod shape, Gram-negative bacterium that causes sepsis (with a greater
than 50% mortality rate), necrotizing fasciitis, gastroenteritis, skin, and soft tissue infection …

Polysaccharides from Dendrobium officinale ameliorate colitis-induced lung injury via inhibiting inflammation and oxidative stress

Y Wen, H Xiao, Y Liu, Y Yang, Y Wang, S Xu… - Chemico-Biological …, 2021 - Elsevier
It has been reported that Dendrobium officinale polysaccharides (DOPS) could alleviate
colitis in animal model and suppress the activation of NLRP3 inflammasome and β-arrestin1 …

Microbiomes in respiratory health and disease: an Asia‐Pacific perspective

SH Chotirmall, SL Gellatly, KF Budden… - …, 2017 - Wiley Online Library
There is currently enormous interest in studying the role of the microbiome in health and
disease. Microbiome's role is increasingly being applied to respiratory diseases, in particular …

Hypoxia‐inducible factor and bacterial infections in chronic obstructive pulmonary disease

SD Shukla, EH Walters, JL Simpson, S Keely… - …, 2020 - Wiley Online Library
ABSTRACT COPD is a seriously disabling respiratory condition that inexorably progresses
to disability and mortality. It affects approximately 10% of the population globally with a …