[HTML][HTML] A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

[HTML][HTML] Natural products for the treatment of depression: Insights into signal pathways influencing the hypothalamic–pituitary–adrenal axis

J Liu, T Meng, C Wang, W Cheng, Q Zhang, G Cheng - Medicine, 2023 - journals.lww.com
Depression, a prevalent psychiatric malady, afflicts a substantial global demographic,
engendering considerable disease burden due to its elevated morbidity and mortality rates …

[HTML][HTML] Microbial Biosynthesis of Chrysazin Derivatives in Recombinant Escherichia coli and Their Biological Activities

PB Poudel, D Dhakal, RT Magar, JK Sohng - Molecules, 2022 - mdpi.com
Anthraquinone and its derivatives show remarkable biological properties such as
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …

Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis

B Liu, C Zhao, Q Xiang, N Zhao, Y Luo… - International Journal of …, 2021 - Elsevier
Glycosylation possess prominent biological and pharmacological significance in natural
product and drug candidate synthesis. The glycosyltransferase YjiC, discovered from …

[HTML][HTML] Antitumoral properties of natural products

R Fabiani - Molecules, 2020 - mdpi.com
Cancer is one of the major causes of death worldwide. It is a multifactorial heterogeneous
disease characterized by a multistep process initiated by genetic alterations of normal cells …

Biocatalytic Synthesis of Non-Natural Monoterpene O-Glycosides Exhibiting Superior Antibacterial and Antinematodal Properties

P Bashyal, RP Pandey, SB Thapa, MK Kang, CJ Kim… - ACS …, 2019 - ACS Publications
A promiscuous Bacillus glycosyltransferase (YjiC) was explored for the enzymatic synthesis
of monoterpene O-glycosides in vitro and in vivo. YjiC converted seven monoterpenes into …

Efficient modification of the Pseudomonas aeruginosa toxin 2-heptyl-1-hydroxyquinolin-4-one by three Bacillus glycosyltransferases with broad substrate ranges

S Thierbach, P Sartor, O Yücel, S Fetzner - Journal of biotechnology, 2020 - Elsevier
Glycosylation of natural and synthetic products can alter the physical, chemical and
pharmacological properties of the aglycon. Conversion of 2-heptyl-1-hydroxyquinolin-4-one …

Regio-specific biotransformation of alizarin to alizarin methoxide with enhanced cytotoxicity against proliferative cells

TTH Nguyen, JM Han, HJ Jung… - Journal of Industrial …, 2020 - academic.oup.com
Alizarin has been reported to have an antigenotoxic activity along with an inhibitory effect on
the tumor cell growth of human colon carcinoma cells. Alizarin was biotransformed into an O …