[HTML][HTML] A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …
[HTML][HTML] Natural products for the treatment of depression: Insights into signal pathways influencing the hypothalamic–pituitary–adrenal axis
J Liu, T Meng, C Wang, W Cheng, Q Zhang, G Cheng - Medicine, 2023 - journals.lww.com
Depression, a prevalent psychiatric malady, afflicts a substantial global demographic,
engendering considerable disease burden due to its elevated morbidity and mortality rates …
engendering considerable disease burden due to its elevated morbidity and mortality rates …
[HTML][HTML] Microbial Biosynthesis of Chrysazin Derivatives in Recombinant Escherichia coli and Their Biological Activities
Anthraquinone and its derivatives show remarkable biological properties such as
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …
Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis
Glycosylation possess prominent biological and pharmacological significance in natural
product and drug candidate synthesis. The glycosyltransferase YjiC, discovered from …
product and drug candidate synthesis. The glycosyltransferase YjiC, discovered from …
[HTML][HTML] Antitumoral properties of natural products
R Fabiani - Molecules, 2020 - mdpi.com
Cancer is one of the major causes of death worldwide. It is a multifactorial heterogeneous
disease characterized by a multistep process initiated by genetic alterations of normal cells …
disease characterized by a multistep process initiated by genetic alterations of normal cells …
Biocatalytic Synthesis of Non-Natural Monoterpene O-Glycosides Exhibiting Superior Antibacterial and Antinematodal Properties
A promiscuous Bacillus glycosyltransferase (YjiC) was explored for the enzymatic synthesis
of monoterpene O-glycosides in vitro and in vivo. YjiC converted seven monoterpenes into …
of monoterpene O-glycosides in vitro and in vivo. YjiC converted seven monoterpenes into …
Efficient modification of the Pseudomonas aeruginosa toxin 2-heptyl-1-hydroxyquinolin-4-one by three Bacillus glycosyltransferases with broad substrate ranges
S Thierbach, P Sartor, O Yücel, S Fetzner - Journal of biotechnology, 2020 - Elsevier
Glycosylation of natural and synthetic products can alter the physical, chemical and
pharmacological properties of the aglycon. Conversion of 2-heptyl-1-hydroxyquinolin-4-one …
pharmacological properties of the aglycon. Conversion of 2-heptyl-1-hydroxyquinolin-4-one …
Regio-specific biotransformation of alizarin to alizarin methoxide with enhanced cytotoxicity against proliferative cells
TTH Nguyen, JM Han, HJ Jung… - Journal of Industrial …, 2020 - academic.oup.com
Alizarin has been reported to have an antigenotoxic activity along with an inhibitory effect on
the tumor cell growth of human colon carcinoma cells. Alizarin was biotransformed into an O …
the tumor cell growth of human colon carcinoma cells. Alizarin was biotransformed into an O …