WD40 repeat proteins: signalling scaffold with diverse functions
BP Jain, S Pandey - The protein journal, 2018 - Springer
The WD40 domain is one of the most abundant and interacting domains in the eukaryotic
genome. In proteins the WD domain folds into a β-propeller structure, providing a platform …
genome. In proteins the WD domain folds into a β-propeller structure, providing a platform …
[HTML][HTML] STRIPAK, a highly conserved signaling complex, controls multiple eukaryotic cellular and developmental processes and is linked with human diseases
U Kück, D Radchenko, I Teichert - Biological chemistry, 2019 - degruyter.com
The striatin-interacting phosphatases and kinases (STRIPAK) complex is evolutionary highly
conserved and has been structurally and functionally described in diverse lower and higher …
conserved and has been structurally and functionally described in diverse lower and higher …
[HTML][HTML] Cellular impacts of striatins and the STRIPAK complex and their roles in the development and metastasis in clinical cancers
Simple Summary The STRIPAK (striatin-interacting phosphatase and kinase) complex and
its central components, striatins (STRNs), have attracted significant interest with regard to …
its central components, striatins (STRNs), have attracted significant interest with regard to …
[HTML][HTML] Striatin family proteins: the neglected scaffolds
The Striatin family of proteins constitutes Striatin, SG2NA, and Zinedin. Members of this
family of proteins act as a signaling scaffold due to the presence of multiple protein-protein …
family of proteins act as a signaling scaffold due to the presence of multiple protein-protein …
The profile of expression of the scaffold protein SG2NA (s) differs between cancer types and its interactome in normal vis-a-vis breast tumor tissues suggests its wide …
Striatin and SG2NA are scaffold proteins that form signaling complexes called STRIPAK. It
has been associated with developmental abnormalities, cancer, and several other diseases …
has been associated with developmental abnormalities, cancer, and several other diseases …
Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMT
SG2NA is a protein of the striatin family that organizes STRIPAK complexes. It has splice
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …
Biophysical characterization of SG2NA variants and their interaction with DJ-1 and calmodulin in vitro
SG2NA was first discovered as nuclear autoantigen in lung and bladder cancer patient. It
was named SG2NA as its expression increases during S to G2 phase of cell cycle …
was named SG2NA as its expression increases during S to G2 phase of cell cycle …
Subcellular dynamics of variants of SG2NA in NIH3T3 fibroblasts
Abstract SG2NA, a WD40 repeat protein of the Striatin subfamily, has four splicing and one
messenger RNA edit variants. It is fast emerging as a scaffold for multimeric signaling …
messenger RNA edit variants. It is fast emerging as a scaffold for multimeric signaling …
[HTML][HTML] 慢性铝暴露致认知障碍血清外泌体miRNAs 差异表达及作用研究
甘珏方， 李莎莎， 王琦， 廉春容， 凌雁武 - Advances in Clinical …, 2022 - hanspub.org
目的: 筛选慢性铝暴露致认知障碍人群, 生信分析其血清外泌体miRNAs 的差异表达,
构建铝致认知障碍miRNA-mRNA 调控网络图, 预测其靶基因. 方法: 筛选广西铝矿区周边某村庄 …
构建铝致认知障碍miRNA-mRNA 调控网络图, 预测其靶基因. 方法: 筛选广西铝矿区周边某村庄 …
[HTML][HTML] Striatin is required for hearing and affects inner hair cells and ribbon synapses
PT Nadar-Ponniah, S Taiber, M Caspi… - Frontiers in Cell and …, 2020 - frontiersin.org
Striatin, a subunit of the serine/threonine phosphatase PP2A, is a core member of the
conserved striatin-interacting phosphatase and kinase (STRIPAK) complexes. The protein is …
conserved striatin-interacting phosphatase and kinase (STRIPAK) complexes. The protein is …