The role of oxytocin in abnormal brain development: effect on glial cells and neuroinflammation
The neonatal period is critical for brain development and determinant for long-term brain
trajectory. Yet, this time concurs with a sensitivity and risk for numerous brain injuries …
trajectory. Yet, this time concurs with a sensitivity and risk for numerous brain injuries …
Validity of mental and physical stress models
E Hendry, B McCallister, DJ Elman, R Freeman… - Neuroscience & …, 2024 - Elsevier
Different stress models are employed to enhance our understanding of the underlying
mechanisms and explore potential interventions. However, the utility of these models …
mechanisms and explore potential interventions. However, the utility of these models …
Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression
M Yoshimura, BP Flynn, YM Kershaw, Z Zhao… - Communications …, 2023 - nature.com
Here we demonstrate, in rodents, how the timing of feeding behaviour becomes disordered
when circulating glucocorticoid rhythms are dissociated from lighting cues; a phenomenon …
when circulating glucocorticoid rhythms are dissociated from lighting cues; a phenomenon …
[HTML][HTML] Chemogenetic Activation of Oxytocin Neurons Improves Pain in a Reserpine-induced Fibromyalgia Rat Model
N Ikeda, M Kawasaki, K Baba, H Nishimura, T Fujitani… - Neuroscience, 2023 - Elsevier
Fibromyalgia (FM) is a syndrome characterized by chronic pain with depression as a
frequent comorbidity. However, efficient management of the pain and depressive symptoms …
frequent comorbidity. However, efficient management of the pain and depressive symptoms …
Deschloroclozapine exhibits an exquisite agonistic effect at lower concentration compared to clozapine-N-oxide in hM3Dq expressing chemogenetically modified rats
M Shimizu, M Yoshimura, K Baba, N Ikeda… - Frontiers in …, 2023 - frontiersin.org
Introduction Within the realm of chemogenetics, a particular form of agonists targeting
designer receptors exclusively activated by designer drugs (DREADDs) has emerged …
designer receptors exclusively activated by designer drugs (DREADDs) has emerged …
Hypothalamic Paraventricular Stimulation Inhibits Nociceptive Wide Dynamic Range Trigeminocervical Complex Cells via Oxytocinergic Transmission
M Condés-Lara, G Martínez-Lorenzana… - Journal of …, 2024 - Soc Neuroscience
Oxytocinergic transmission blocks nociception at the peripheral, spinal, and supraspinal
levels through the oxytocin receptor (OTR). Indeed, a neuronal pathway from the …
levels through the oxytocin receptor (OTR). Indeed, a neuronal pathway from the …
Oxytocin as neuro-hormone and neuro-regulator exert neuroprotective properties: a mechanistic graphical review
R Kamrani-Sharif, AW Hayes, M Gholami, M Salehirad… - Neuropeptides, 2023 - Elsevier
Background Neurodegeneration is progressive cell loss in specific neuronal populations,
often resulting in clinical consequences with significant medical, societal, and economic …
often resulting in clinical consequences with significant medical, societal, and economic …
Oxytocin: A multi-functional biomolecule with potential actions in dysfunctional conditions; from animal studies and beyond
AS Tsingotjidou - Biomolecules, 2022 - mdpi.com
Oxytocin is a hormone secreted from definite neuroendocrine neurons located in specific
nuclei in the hypothalamus (mainly from paraventricular and supraoptic nuclei), and its main …
nuclei in the hypothalamus (mainly from paraventricular and supraoptic nuclei), and its main …
The psychophysiology of music-based interventions and the experience of pain
CA Arnold, MK Bagg, AR Harvey - Frontiers in Psychology, 2024 - frontiersin.org
In modern times there is increasing acceptance that music-based interventions are useful
aids in the clinical treatment of a range of neurological and psychiatric conditions, including …
aids in the clinical treatment of a range of neurological and psychiatric conditions, including …
Chronic Pain–Related Cognitive Deficits: Preclinical Insights into Molecular, Cellular, and Circuit Mechanisms
S Han, J Wang, W Zhang, X Tian - Molecular Neurobiology, 2024 - Springer
Cognitive impairment is a common comorbidity of chronic pain, significantly disrupting
patients' quality of life. Despite this comorbidity being clinically recognized, the underlying …
patients' quality of life. Despite this comorbidity being clinically recognized, the underlying …