Human body-fluid proteome: quantitative profiling and computational prediction

L Huang, D Shao, Y Wang, X Cui, Y Li… - Briefings in …, 2021 - academic.oup.com
Empowered by the advancement of high-throughput bio technologies, recent research on
body-fluid proteomes has led to the discoveries of numerous novel disease biomarkers and …

Sample preparation techniques for the untargeted LC‐MS‐based discovery of peptides in complex biological matrices

I Finoulst, M Pinkse, W Van Dongen… - BioMed Research …, 2011 - Wiley Online Library
Although big progress has been made in sample pretreatment over the last years, there are
still considerable limitations when it comes to overcoming complexity and dynamic range …

Multivariate curve resolution of hyphenated and multidimensional chromatographic measurements: a new insight to address current chromatographic challenges

H Parastar, R Tauler - 2014 - ACS Publications
In this Feature, the capabilities and versatility of multivariate curve resolution methods are
discussed in light of the current challenges in chromatographic measurements, with special …

Intact protein separation by chromatographic and/or electrophoretic techniques for top-down proteomics

AL Capriotti, C Cavaliere, P Foglia, R Samperi… - … of Chromatography A, 2011 - Elsevier
Mass spectrometry used in combination with a wide variety of separation methods is the
principal methodology for proteomics. In bottom-up approach, proteins are cleaved with a …

MS‐based analytical methodologies to characterize genetically modified crops

V García‐Cañas, C Simó, C León… - Mass spectrometry …, 2011 - Wiley Online Library
The development of genetically modified crops has had a great impact on the agriculture
and food industries. However, the development of any genetically modified organism (GMO) …

Nano‐LC: An updated review

L Shan, BR Jones - Biomedical Chromatography, 2022 - Wiley Online Library
Low‐flow chromatography has a rich history of innovation but has yet to reach widespread
implementation in bioanalytical applications. Improvements in pump technology, microfluidic …

Recent advances in on-line multidimensional liquid chromatography

H Malerod, E Lundanes, T Greibrokk - Analytical Methods, 2010 - pubs.rsc.org
Multidimensional liquid chromatography (MD LC) has, due to enhanced peak capacity
compared to one-dimensional LC, become an important analytical tool for separating …

Construction of a microfluidic platform integrating online protein fractionation, denaturation, digestion, and peptide enrichment

ZH Wei, X Zhang, X Zhao, YJ Jiao, YP Huang, ZS Liu - Talanta, 2021 - Elsevier
Microfluidic system with multi-functional integration of high-throughput protein/peptide
separation ability has great potential for improving the identification capacity of biological …

Chromatography

DS Hage - Principles and applications of clinical mass …, 2018 - Elsevier
Background Clinical tests often involve the use of one or more separation steps to isolate,
enrich, or separate a target compound from other chemicals in the sample. Chromatography …

Hyphenated separation techniques for complex polymers

H Pasch - Polymer Chemistry, 2013 - pubs.rsc.org
Complex polymers are distributed in more than one direction of molecular heterogeneity. In
addition to the molar mass distribution, they are frequently distributed with respect to …