Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model …

H Chi, E Messas, RA Levine, DT Graves, S Amar - Circulation, 2004 - Am Heart Assoc
Background—Current data demonstrate that progressive atherosclerosis is associated with
activation of the inflammatory process, as evidenced by systemic elevations of molecules …

Cytokine-related aging process

JE Morley, RN Baumgartner - The Journals of Gerontology …, 2004 - academic.oup.com
CYTOKINES are soluble peptide messengers that are synthesized by lymphocytes (thus,
they were originally called lymphokines), neutrophils, macrophages, and neuronal cells. The …

Anti-inflammatory and antiobesity effects of mulberry leaf and fruit extract on high fat diet-induced obesity

HH Lim, SO Lee, SY Kim, SJ Yang… - … Biology and Medicine, 2013 - journals.sagepub.com
The purpose of this study was to investigate the anti-inflammatory and antiobesity effect of
combinational mulberry leaf extract (MLE) and mulberry fruit extract (MFE) in a high-fat (HF) …

Heart protective effects and mechanism of quercetin preconditioning on anti-myocardial ischemia reperfusion (IR) injuries in rats

H Liu, X Guo, Y Chu, S Lu - Gene, 2014 - Elsevier
In this study, we investigated the effects and mechanism of quercetin preconditioning on anti-
myocardial ischemia reperfusion (IR) injuries in vivo. Meanwhile, their potential anti …

miR-146a polymorphism influences levels of miR-146a, IRAK-1, and TRAF-6 in young patients with coronary artery disease

P Ramkaran, S Khan, A Phulukdaree… - Cell biochemistry and …, 2014 - Springer
Modulation of nuclear factor KappaB (NF-κB) activation may play a role in regulating
inflammatory conditions associated with coronary artery disease (CAD). MicroRNA-146a …

Excess recurrent cardiac events in rheumatoid arthritis patients with acute coronary syndrome

KMJ Douglas, AV Pace, GJ Treharne… - Annals of the …, 2006 - ard.bmj.com
Background: Cardiovascular mortality is increased in rheumatoid arthritis. Possible reasons
include an increased incidence of ischaemic heart disease or worse outcome after acute …

The long pentraxin PTX3 in vascular pathology

A Mantovani, C Garlanda, B Bottazzi, G Peri… - Vascular …, 2006 - Elsevier
Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition
proteins characterized by a cyclic multimeric structure. Based on the primary structure of the …

Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore–induced allergic airway disease

AP Moreira, KA Cavassani, R Hullinger… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Aspergillus fumigatus conidia aggravate asthmatic responses. Lung
macrophages normally kill fungal conidia, but the presence of type 2 cytokines during …

Pattern recognition by pentraxins

A Agrawal, PP Singh, B Bottazzi, C Garlanda… - … pattern recognition in …, 2009 - Springer
Pentraxins are a family of evolutionarily conserved pattern-recognition proteins that are
made up of five identical subunits. Based on the primary structure of the subunit, the …

Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice

GM Hirschfield, JR Gallimore… - Proceedings of the …, 2005 - National Acad Sciences
The association between circulating concentrations of C-reactive protein (CRP) and future
atherothrombotic events has provoked speculation about a possible pathogenetic role of …