There are now more Americans older than 65 years than at any other point in US history,
and the aging population is expected to increase rapidly over the next decade. 1 Aging …

Airway nerves represent a mechanistically and therapeutically important aspect that requires
better highlighting in the context of diseases such as asthma. Altered structure and function …

Background Asthma is a common chronic airway disease worldwide. Despite its large
population size, China has had no comprehensive study of the national prevalence, risk …

Cellular senescence results in cell cycle arrest with secretion of cytokines, chemokines,
growth factors, and remodeling proteins (senescence-associated secretory phenotype; …

Although the hallmark features of asthma include reversible airflow obstruction, airway
eosinophilia, and symptoms of recurrent wheeze associated with breathlessness and cough …

Senescent cells can drive age-related tissue dysfunction partially via a senescence-
associated secretory phenotype (SASP) involving proinflammatory and profibrotic factors …

Background Emerging evidence suggests that aging affects asthma outcomes, but the
mechanism remains largely unexplored. Objective To explore age-related clinical …

Das Management von Asthma hat sich in den letzten Jahrzehnten fundamental gewandelt.
Die vorliegende Leitlinie zur Diagnostik und Therapie von Asthma wurde für pneumologisch …

Frailty is a complex, multidimensional syndrome characterised by a loss of physiological
reserves that increases a person9s susceptibility to adverse health outcomes. Most …

Background Data regarding medication adherence in older adults with asthma before and
during the coronavirus disease 2019 (COVID-19) pandemic are lacking. Objective To …