Treatable traits in elderly asthmatics from the Australasian Severe Asthma Network: a prospective cohort study

WW Wu, X Zhang, M Li, Y Liu, ZH Chen, M Xie… - The Journal of Allergy …, 2021 - Elsevier
Background Data on treatable traits (TTs) in different populations are limited. Objective To
assess TTs in elderly patients with asthma and compare them to younger patients, to …

Asthma in the elderly

SS Braman - Clinics in geriatric medicine, 2017 - geriatric.theclinics.com
Asthma was long considered a childhood disease. There was little focus on asthma in
elderly subjects until the Tucson epidemiologic study of obstructive lung disease brought …

Effectiveness and safety of inhaled corticosteroids in older individuals with chronic obstructive pulmonary disease and/or asthma. A population study

T Kendzerska, SD Aaron, T To, C Licskai… - Annals of the …, 2019 - atsjournals.org
Rationale: Inhaled corticosteroids (ICS) are established medications for the management of
both asthma and chronic obstructive pulmonary disease (COPD), two common chronic …

Heterogeneity of paucigranulocytic asthma: a prospective cohort study with hierarchical cluster analysis

K Deng, X Zhang, Y Liu, L Zhang, G Wang… - The Journal of Allergy …, 2021 - Elsevier
Background Asthma, a heterogeneous disease, can be divided into 4 inflammatory
phenotypes using induced sputum cell counts—eosinophilic asthma (EA), neutrophilic …

[HTML][HTML] Ambient particulate matter associates with asthma in high altitude region: A population-based study

ZZ Xing, T Yang, S Shi, X Meng, R Chen, H Long… - World Allergy …, 2023 - Elsevier
Background Exposure to particulate matter (PM) has been a major public health threat, but
the potentially differential effects on asthma of PM remain largely unknown in high altitude …

The stress of lung aging: Endoplasmic reticulum and senescence Tete-a-Tete

ML Koloko Ngassie, CA Brandsma, R Gosens… - …, 2021 - journals.physiology.org
Beyond the structural changes, features including the dysregulation of endoplasmic
reticulum (ER) stress response and increased senescence characterize the lung aging. ER …

Metabolic phenotypes in asthmatic adults: Relationship with inflammatory and clinical phenotypes and prognostic implications

A Santos, H Pité, C Chaves-Loureiro, SM Rocha… - Metabolites, 2021 - mdpi.com
Bronchial asthma is a chronic disease that affects individuals of all ages. It has a high
prevalence and is associated with high morbidity and considerable levels of mortality …

Diagnostic and therapeutic approaches for elderly asthma patients: the importance of multidisciplinary and multidimensional management

A Benfante, A Tomasello, E Gianquinto… - Expert Review of …, 2023 - Taylor & Francis
Introduction Asthma is commonly considered a disease of younger ages; however, it is not
infrequent to pose a diagnosis of the disease in older individuals. Although current …

Global burden of asthma associated with high body mass index from 1990 to 2019

J Liu, M Yuan, Y Chen, Y Wang, Q Wang… - Annals of Allergy …, 2022 - Elsevier
Background High body mass index (BMI) plays a key role in the progression of asthma and
asthma related to high BMI resulted in a high burden of disease globally. Objective To …

Safety of biological therapy in elderly patients with severe asthma

P Mir-Ihara, E Narvaez-Fernandez… - Journal of …, 2022 - Taylor & Francis
Objective To assess the safety of biological therapy for severe T2 asthma (omalizumab,
mepolizumab, benralizumab and reslizumab) under real-life conditions in elderly patients …