P2X receptors are membrane ion channels that open in response to the binding of
extracellular ATP. Seven genes in vertebrates encode P2X receptor subunits, which are 40 …

Mammalian ATP-gated nonselective cation channels (P2XRs) can be composed of seven
possible subunits, denoted P2X1 to P2X7. Each subunit contains a large ectodomain, two …

P2X receptors are cation-selective ion channels gated by extracellular ATP, and are
implicated in diverse physiological processes, from synaptic transmission to inflammation to …

P2X receptors are membrane cation channels gated by extracellular ATP. Seven P2X
receptor subunits (P2X1-7) are widely distributed in excitable and nonexcitable cells of …

P2X receptors are ATP-gated cation channels with important roles in diverse
pathophysiological processes. Substantial progress has been made in the last few years …

Abstract ATP-gated P2X receptors are trimeric ion channels that assemble as homo-or
heteromers from seven cloned subunits. Transcripts and/or proteins of P2X subunits have …

Seven P2X receptor subunits have been cloned which form functional homo-and
heterotrimers. These are cation-selective channels, equally permeable to Na+ and K+ and …

Abstract P2X7 receptor (P2X7R), a distinct ligand-gated ion channel, is a member of
purinergic type 2 receptor family with ubiquitous expression in human body. Previous …

ATP-gated ionotropic receptors (P2X receptors) are distributed widely in the nervous system.
For example, a hetero-oligomeric receptor containing both P2X2 and P2X3 subunits is …

P2X receptors for adenosine tri-phosphate (ATP) are a distinct family of ligand-gated cation
channels with two transmembrane domains, intracellular amino and carboxy termini and a …