Cutaneous squamous cell carcinoma: review of the eighth edition of the American Joint Committee on cancer staging guidelines, prognostic factors, and …

K Motaparthi, JP Kapil… - Advances in Anatomic …, 2017 - journals.lww.com
Cutaneous squamous cell carcinoma is the second most common form of nonmelanoma
skin cancer after basal cell carcinoma and accounts for the majority of nonmelanoma skin …

Advances in the pathology of penile carcinomas

A Chaux, AL Cubilla - Human pathology, 2012 - Elsevier
The incidence of penile cancer varies from country to country, with the highest figures
reported for countries in Africa, South America, and Asia and lowest in the United States and …

Whole-exome sequencing in penile squamous cell carcinoma uncovers novel prognostic categorization and drug targets similar to head and neck squamous cell …

J Chahoud, FO Gleber-Netto, BZ McCormick… - Clinical Cancer …, 2021 - AACR
Purpose: Penile squamous cell carcinoma (PSCC) is rare with limited treatment options. We
report the first whole-exome sequencing (WES) analysis and compare the molecular …

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53 …

S Mannweiler, S Sygulla, E Winter… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Penile squamous cell carcinomas (SCC) arise either through transforming
infections with human papillomavirus (HPV) or independent of HPV, often in the background …

Value of p16INK4a in the pathology of invasive penile squamous cell carcinomas: a report of 202 cases

AL Cubilla, B Lloveras, M Alejo, O Clavero… - The American journal …, 2011 - journals.lww.com
Background One third to one half of penile squamous cell carcinomas (SCCs) are related to
human papillomavirus (HPV) infection. Viral detection is usually carried out by polymerase …

The molecular pathogenesis of penile carcinoma—current developments and understanding

A Emmanuel, J Nettleton, N Watkin, DM Berney - Virchows Archiv, 2019 - Springer
Penile squamous cell carcinoma is a rare malignancy with various distinct histological
subtypes, each with distinct appearances, histotypic specific associations with human …

Pathogenesis of penile squamous cell carcinoma: molecular update and systematic review

I Ribera-Cortada, J Guerrero-Pineda, I Trias… - International Journal of …, 2021 - mdpi.com
Penile squamous cell carcinoma (PSCC) is a rare but aggressive neoplasm with dual
pathogenesis (human papillomavirus (HPV)-associated and HPV-independent). The …

Distribution and characterization of subtypes of penile intraepithelial neoplasia and their association with invasive carcinomas: a pathological study of 139 lesions in …

A Chaux, EF Velazquez, A Amin, A Soskin, R Pfannl… - Human pathology, 2012 - Elsevier
We are presenting the morphological features of 121 cases of atypical penile intraepithelial
lesions. The term penile intraepithelial neoplasia (PeIN) was used to encompass all of them …

The role of human papilloma virus in penile carcinogenesis and preneoplastic lesions: a potential target for vaccination and treatment strategies

GJ Diorio, AR Giuliano - Urologic Clinics, 2016 - urologic.theclinics.com
Although rare, penile cancer is a devastating disease, especially at advanced stages. The
overall incidence in the United States and Western Europe is low, estimated to be 0.4% of all …

The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

J Steinestel, A Al Ghazal, A Arndt, TJ Schnoeller… - BMC cancer, 2015 - Springer
Background Up to 50% of penile squamous cell carcinomas (pSCC) develop in the context
of high-risk human papillomavirus (HR-HPV) infection. Most of these tumours have been …