Peroxisome biogenesis
PE Purdue, PB Lazarow - Annual review of cell and …, 2001 - annualreviews.org
▪ Abstract Fifteen years ago, we had a model of peroxisome biogenesis that involved growth
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …
Peroxisome biogenesis disorders
S Weller, SJ Gould, D Valle - Annual review of genomics and …, 2003 - annualreviews.org
The peroxisome biogenesis disorders (PBDs) comprise 12 autosomal recessive
complementation groups (CGs). The multisystem clinical phenotype varies widely in severity …
complementation groups (CGs). The multisystem clinical phenotype varies widely in severity …
[HTML][HTML] Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery
B Agne, NM Meindl, K Niederhoff, H Einwächter… - Molecular cell, 2003 - cell.com
Peroxisomes transport folded and oligomeric proteins across their membrane. Two cytosolic
import receptors, Pex5p and Pex7p, along with approximately 12 membrane-bound …
import receptors, Pex5p and Pex7p, along with approximately 12 membrane-bound …
[HTML][HTML] The human peroxisomal targeting signal receptor, Pex5p, is translocated into the peroxisomal matrix and recycled to the cytosol
V Dammai, S Subramani - Cell, 2001 - cell.com
Peroxisomal targeting signals (PTSs) are recognized by predominantly cytosolic receptors,
Pex5p and Pex7p. The fate of these PTS receptors following their interactions on the …
Pex5p and Pex7p. The fate of these PTS receptors following their interactions on the …
Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p …
H Otera, K Setoguchi, M Hamasaki… - … and cellular biology, 2002 - Taylor & Francis
Two isoforms of the peroxisomal targeting signal type 1 (PTS1) receptor, termed Pex5pS
and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 …
and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 …
Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export
N Miyata, Y Fujiki - Molecular and cellular biology, 2005 - Taylor & Francis
Peroxisomal matrix proteins are posttranslationally imported into peroxisomes with the
peroxisome-targeting signal 1 receptor, Pex5. The longer isoform of Pex5, Pex5L, also …
peroxisome-targeting signal 1 receptor, Pex5. The longer isoform of Pex5, Pex5L, also …
The pathogenic peroxin Pex26p recruits the Pex1p–Pex6p AAA ATPase complexes to peroxisomes
N Matsumoto, S Tamura, Y Fujiki - Nature cell biology, 2003 - nature.com
Peroxisomes are ubiquitous organelles with a single membrane that contain over 50
different enzymes that catalyse various metabolic pathways, including β-oxidation and lipid …
different enzymes that catalyse various metabolic pathways, including β-oxidation and lipid …
Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders
RJA Wanders, HR Waterham - Clinical genetics, 2005 - Wiley Online Library
The peroxisomal disorders represent a group of genetic diseases in humans in which there
is an impairment in one or more peroxisomal functions. The peroxisomal disorders are …
is an impairment in one or more peroxisomal functions. The peroxisomal disorders are …
[HTML][HTML] The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation
K Okumoto, M El Shermely, M Natsui, H Kosako… - Elife, 2020 - elifesciences.org
Most of peroxisomal matrix proteins including a hydrogen peroxide (H2O2)-decomposing
enzyme, catalase, are imported in a peroxisome-targeting signal type-1 (PTS1)-dependent …
enzyme, catalase, are imported in a peroxisome-targeting signal type-1 (PTS1)-dependent …
Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences
M Fransen, T Wylin, C Brees… - … and cellular biology, 2001 - Taylor & Francis
The molecular machinery underlying peroxisomal membrane biogenesis is not well
understood. The observation that cells deficient in the peroxins Pex3p, Pex16p, and Pex19p …
understood. The observation that cells deficient in the peroxins Pex3p, Pex16p, and Pex19p …