Innate immunity: the first line of defense against SARS-CoV-2
MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
Acute pancreatitis: diagnosis and treatment
P Szatmary, T Grammatikopoulos, W Cai, W Huang… - Drugs, 2022 - Springer
Acute pancreatitis is a common indication for hospital admission, increasing in incidence,
including in children, pregnancy and the elderly. Moderately severe acute pancreatitis with …
including in children, pregnancy and the elderly. Moderately severe acute pancreatitis with …
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …
[HTML][HTML] Programmed cell death tunes tumor immunity
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …
the years revealed distinctive molecular mechanisms and functional consequences of …
[PDF][PDF] Mucosal immune responses to infection and vaccination in the respiratory tract
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …
Programming inflammatory cell death for therapy
S Christgen, RE Tweedell, TD Kanneganti - Pharmacology & therapeutics, 2022 - Elsevier
Programmed cell death (PCD) is an essential part of organismal development and plays
fundamental roles in host defense against pathogens and the maintenance of homeostasis …
fundamental roles in host defense against pathogens and the maintenance of homeostasis …
[HTML][HTML] From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways
Y Wang, TD Kanneganti - Computational and structural biotechnology …, 2021 - Elsevier
Pyroptosis, apoptosis and necroptosis are the most genetically well-defined programmed
cell death (PCD) pathways, and they are intricately involved in both homeostasis and …
cell death (PCD) pathways, and they are intricately involved in both homeostasis and …
Innate immune cell death in neuroinflammation and Alzheimer's disease
Y Rajesh, TD Kanneganti - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder molecularly characterized by the
formation of amyloid β (Aβ) plaques and type 2 microtubule-associated protein (Tau) …
formation of amyloid β (Aβ) plaques and type 2 microtubule-associated protein (Tau) …
mRNA lipid nanoparticle-mediated pyroptosis sensitizes immunologically cold tumors to checkpoint immunotherapy
Synergistically improving T-cell responsiveness is promising for favorable therapeutic
outcomes in immunologically cold tumors, yet current treatments often fail to induce a …
outcomes in immunologically cold tumors, yet current treatments often fail to induce a …
It's all in the PAN: crosstalk, plasticity, redundancies, switches, and interconnectedness encompassed by PANoptosis underlying the totality of cell death-associated …
JM Gullett, RE Tweedell, TD Kanneganti - Cells, 2022 - mdpi.com
The innate immune system provides the first line of defense against cellular perturbations.
Innate immune activation elicits inflammatory programmed cell death in response to …
Innate immune activation elicits inflammatory programmed cell death in response to …