Glioblastoma microenvironment and cellular interactions

CB Crivii, AB Boșca, CS Melincovici, AM Constantin… - Cancers, 2022 - mdpi.com
Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Signaling pathways governing glioma cancer stem cells behavior

A Nasrolahi, S Azizidoost, K Radoszkiewicz, S Najafi… - Cellular …, 2023 - Elsevier
Glioma is the most common malignant brain tumor that develops in the glial tissue. Several
studies have identified that glioma cancer stem cells (GCSCs) play important roles in tumor …

Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review

AA Arabzadeh, T Mortezazadeh, T Aryafar… - Cancer cell …, 2021 - Springer
Glioblastoma, WHO grade IV astrocytoma, is the most aggressive type of brain tumors.
These cancerous cells have a rapid growth rate, tendency to penetrate vital brain structures …

Advancing glioblastoma imaging: Exploring the potential of organic fluorophore-based red emissive carbon dots

JB Domena, BCLB Ferreira, EK Cilingir, Y Zhou… - Journal of colloid and …, 2023 - Elsevier
Over time, the interest in developing stable photosensitizers (PS) which both absorb and
emit light in the red region (650 and 950 nm) has gained noticeable interest. Recently …

Nanomedicines targeting glioma stem cells

A Sabu, TI Liu, SS Ng, RA Doong… - … Applied Materials & …, 2022 - ACS Publications
Glioblastoma (GBM), classified as a grade IV glioma, is a rapidly growing, aggressive, and
most commonly occurring tumor of the central nervous system. Despite the therapeutic …

Digging the intercellular crosstalkviaextracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?

A Macedo-Pereira, C Martins, J Lima… - … Clinics and Research, 2023 - journals.lww.com
Glioblastoma (GBM) is an adult's most aggressive brain tumor. The advances in molecular
pathology and cell signaling pathways have deepened researchers' understanding of …

[HTML][HTML] The promise of niacin in neurology

E Wuerch, GR Urgoiti, VW Yong - Neurotherapeutics, 2023 - Elsevier
Niacin (vitamin B3) is an essential nutrient that treats pellagra, and prior to the advent of
statins, niacin was commonly used to counter dyslipidemia. Recent evidence has posited …

Non-coding RNAs and glioma: Focus on cancer stem cells

A Rajabi, M Kayedi, S Rahimi, F Dashti… - Molecular Therapy …, 2022 - cell.com
Glioblastoma and gliomas can have a wide range of histopathologic subtypes. These
heterogeneous histologic phenotypes originate from tumor cells with the distinct functions of …

Molecular pathways and genomic landscape of glioblastoma stem cells: opportunities for targeted therapy

AM Hersh, H Gaitsch, S Alomari, D Lubelski, BM Tyler - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma stem cells are a unique population of tumor cells that
contribute to tumor growth, invasion, and resistance to chemotherapy and radiation therapy …

Investigating the Interactions of Glioma Stem Cells in the Perivascular Niche at Single‐Cell Resolution using a Microfluidic Tumor Microenvironment Model

EA Adjei‐Sowah, SA O'Connor, J Veldhuizen… - Advanced …, 2022 - Wiley Online Library
The perivascular niche (PVN) is a glioblastoma tumor microenvironment (TME) that serves
as a safe haven for glioma stem cells (GSCs), and acts as a reservoir that inevitably leads to …