Adiponectin and its role in cardiovascular diseases

J Beltowski, A Jamroz-Wisniewska… - … Formerly Current Drug …, 2008 - ingentaconnect.com
Studies performed during the last decade indicate that adipose tissue is not only a site of
triglyceride storage but also an active endocrine organ which secretes many biologically …

[PDF][PDF] Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs

CA Glastonbury, AC Alves, JSES Moustafa… - The American Journal of …, 2019 - cell.com
Adipose tissue is an important endocrine organ with a role in many cardiometabolic
diseases. It is comprised of a heterogeneous collection of cell types that can differentially …

Young and elderly patients with type 2 diabetes have optimal B cell responses to the seasonal influenza vaccine

D Frasca, A Diaz, M Romero, NV Mendez, AM Landin… - Vaccine, 2013 - Elsevier
We evaluated immune response to the seasonal influenza vaccine in young and elderly
patients with type 2 diabetes (T2D). Immune measures included the in vivo serum response …

Metabolic phenotypes, vascular complications, and premature deaths in a population of 4,197 patients with type 1 diabetes

VP Makinen, C Forsblom, LM Thorn, J Wadén… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Poor glycemic control, elevated triglycerides, and albuminuria are associated
with vascular complications in diabetes. However, few studies have investigated combined …

Hyperuricaemia and the metabolic syndrome in type 2 DM

AO Ogbera, AO Azenabor - Diabetology & metabolic syndrome, 2010 - Springer
Background Elevated serum uric acid levels (SUA) have been associated with an increased
risk of cardiovascular diseases and the metabolic syndrome (MetS) and are often reported to …

Intermittent Hypoxia Up-Regulates CCL2, RETN, and TNFα mRNAs in Adipocytes via Down-regulation of miR-452

T Uchiyama, A Itaya-Hironaka, A Yamauchi… - International Journal of …, 2019 - mdpi.com
Sleep apnea syndrome (SAS), characterized by recurrent episodes of oxygen desaturation
and reoxygenation (intermittent hypoxia [IH]), is a risk factor for insulin resistance. Recently …

EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet [S]

A Pinel, E Pitois, JP Rigaudiere, C Jouve… - Journal of lipid …, 2016 - ASBMB
The impact of alpha linolenic acid (ALA), EPA, and DHA on obesity and metabolic
complications was studied in mice fed a high-fat, high-sucrose (HF) diet. HF diets were …

Visceral adiposity predicts severity of acute pancreatitis

A Natu, T Stevens, L Kang, S Yasinow, E Mansoor… - Pancreas, 2017 - journals.lww.com
Objectives The aim of this study was to determine the association of visceral adiposity with
severe outcomes in acute pancreatitis (AP). Methods This retrospective study included …

A mouse model of metabolic syndrome; increase in visceral adipose tissue precedes the development of fatty liver and insulin resistance in high-fat diet-fed male KK …

S Akagiri, Y Naito, H Ichikawa, K Mizushima… - Journal of clinical …, 2008 - jstage.jst.go.jp
抄録 To determine the relative contribution of obesity and visceral white adipose tissue
(WAT) to metabolic syndrome, we developed a model that is susceptible to high-fat diet …

Adipokines and hepatic insulin resistance

Y Li, L Ding, W Hassan, D Abdelkader… - Journal of diabetes …, 2013 - Wiley Online Library
Obesity is a major risk factor for insulin resistance and type 2 diabetes. Adipose tissue is
now considered to be an active endocrine organ that secretes various adipokines such as …