Chitinase-3–like protein 1 (CHI3L1) is primarily secreted by activated astrocytes in the brain
and is known as a reliable biomarker for inflammatory central nervous system (CNS) …

Neuromyelitis optica spectrum disorder (NMOSD) is a severe form of inflammation of the
central nervous system (CNS) including acute myelitis, optic neuritis and brain syndrome …

Objective Astrocytes outline the perivascular space (PVS) and regulate fluid exchange
through the aquaporin‐4 water channel. As neuromyelitis optica is an autoimmune …

Neuromyelitis optica (NMO) arises from primary astrocytopathy induced by autoantibodies
targeting the astroglial protein aquaporin 4 (AQP4), leading to severe neurological sequelae …

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disease
of the central nervous system. However, whether and how cortical changes occur in NMOSD …

Background Spinal cord and brain atrophy are common in neuromyelitis optica spectrum
disorder (NMOSD) and relapsing-remitting multiple sclerosis (RRMS) but harbor distinct …

Background Learning complex navigation routes increases hippocampal volume in humans,
but it is not clear whether this growth impacts behaviors outside the learning situation or …

Aims Many patients with neuromyelitis optica spectrum disorders (NMOSD) suffer from
cognitive impairment affecting memory, processing speed and attention and suffer from …

伴有脑损伤的视神经脊髓炎谱系疾病患者存在严重的丘脑萎缩, 但无明显脑病灶的视神经脊髓炎
谱系疾病患者是否出现皮质萎缩, 其皮质改变与其临床特征相关性目前尚不完全明确. 为此 …

The aim was to examine the diagnostic efficacy of hippocampal subregions volume and
texture in differentiating amnestic mild cognitive impairment (MCI) from normal aging …