Imaging findings in craniofacial childhood rhabdomyosarcoma

NJM Freling, JHM Merks, P Saeed, AJM Balm, J Bras… - Pediatric …, 2010 - Springer
Rhabdomyosarcoma (RMS) is the commonest paediatric soft-tissue sarcoma constituting 3–
5% of all malignancies in childhood. RMS has a predilection for the head and neck area and …

Myogenesis and rhabdomyosarcoma: the jekyll and hyde of skeletal muscle

R Saab, SL Spunt, SX Skapek - Current topics in developmental biology, 2011 - Elsevier
Rhabdomyosarcoma, a neoplasm composed of skeletal myoblast-like cells, represents the
most common soft tissue sarcoma in children. The application of intensive …

Comparison of PET–CT and conventional imaging in staging pediatric rhabdomyosarcoma

SM Federico, SL Spunt, MJ Krasin… - Pediatric blood & …, 2013 - Wiley Online Library
Background Over the past decade, PET–CT has been used to assess rhabdomyosarcoma
(RMS) in children. However, the role of PET–CT in staging RMS is unknown. Procedure …

Head and neck sarcomas: epidemiology, pathology, and management

JP O'Neill, MH Bilsky, D Kraus - Neurosurgery Clinics, 2013 - neurosurgery.theclinics.com
Head and neck sarcomas are a diverse group of cancers. According to the American Cancer
Society, in 2010 10,520 new sarcomas were predicted to occur, with 3920 deaths. Head and …

Prognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group

DA Rodeberg, N Garcia-Henriquez… - Journal of Clinical …, 2011 - ascopubs.org
Purpose Regional lymph node disease (RLND) is a component of the risk-based treatment
stratification in rhabdomyosarcoma (RMS). The purpose of this study was to determine the …

Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study

E Bompas, L Campion, A Italiano, A Le Cesne… - Cancer …, 2018 - Wiley Online Library
Five‐year overall survival (OS) of localized RMS exceeds 70% in children (< 18) but is very
poor in adult patients. We analyzed the outcome and prognostic factors (PF) of a national …

Artesunate induces ROS- and p38 MAPK-mediated apoptosis and counteracts tumor growth in vivo in embryonal rhabdomyosarcoma cells

S Beccafico, G Morozzi, MC Marchetti… - …, 2015 - academic.oup.com
Rhabdomyosarcoma represents about 50% of soft-tissue sarcomas and 10% of malignant
solid tumors in childhood. Embryonal rhabdomyosarcoma (ERMS) is the most frequent …

Update on pediatric rhabdomyosarcoma: A report from the APSA Cancer Committee

DS Rhee, DA Rodeberg, RM Baertschiger… - Journal of pediatric …, 2020 - Elsevier
Abstract Background/Purpose Rhabdomyosarcoma is the most common soft tissue sarcoma
in children and young adults and requires multimodality treatment. The purpose of this …

[HTML][HTML] Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo

S Yan, Z Li, CJ Thiele - Oncotarget, 2013 - ncbi.nlm.nih.gov
Abstract The IL-6/JAK/STAT pathway is a key signal transduction pathway implicated in the
pathogenesis of many human cancers, suggesting that kinase inhibitors targeting …

Fusion status in patients with lymph node‐positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft …

S Gallego, I Zanetti, D Orbach, D Ranchère, J Shipley… - Cancer, 2018 - Wiley Online Library
BACKGROUND Alveolar rhabdomyosarcoma (aRMS) with lymph node involvement (N1
classification) accounts for up to 10% of all cases of RMS. The prognosis is poor, and is …