[HTML][HTML] The role of cGAS-STING signalling in liver diseases

R Chen, J Du, H Zhu, Q Ling - Jhep Reports, 2021 - Elsevier
The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS)
activates the downstream adaptor protein stimulator of interferon genes (STING) by …

Shaping of hepatic ischemia/reperfusion events: the crucial role of mitochondria

JS Teodoro, RT Da Silva, IF Machado… - Cells, 2022 - mdpi.com
Hepatic ischemia reperfusion injury (HIRI) is a major hurdle in many clinical scenarios,
including liver resection and transplantation. Various studies and countless surgical events …

[PDF][PDF] Cordycepin ameliorates nonalcoholic steatohepatitis by activation of the AMP‐activated protein kinase signaling pathway

T Lan, Y Yu, J Zhang, H Li, Q Weng, S Jiang… - …, 2021 - Wiley Online Library
Background and Aims Nonalcoholic fatty liver disease, especially nonalcoholic
steatohepatitis (NASH), has become a major cause of liver transplantation and liver …

KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy

J Li, D Yu, C He, Q Yu, Z Huo, Y Zhang… - Cell Death & Disease, 2023 - nature.com
Hepatic ischemia-reperfusion (I/R) injury, a common clinical complication of liver
transplantation, gravely affects patient prognosis. Krüppel-like factors (KLFs) constitute a …

Cordycepin protects against acute pancreatitis by modulating NF-κB and NLRP3 inflammasome activation via AMPK

J Yang, Y Zhou, J Shi - Life sciences, 2020 - Elsevier
Acute pancreatitis (AP) is a noninfectious inflammatory disease with high morbidity and
mortality, which is characterized by severe inflammation and tissue necrosis. Cordycepin …

The effect of hypothermic machine perfusion to ameliorate ischemia-reperfusion injury in donor organs

LWD Knijff, C van Kooten, RJ Ploeg - Frontiers in Immunology, 2022 - frontiersin.org
Hypothermic machine perfusion (HMP) has become the new gold standard in clinical donor
kidney preservation and a promising novel strategy in higher risk donor livers in several …

[HTML][HTML] Copper induces mitochondria-mediated apoptosis via AMPK-mTOR pathway in hypothalamus of Pigs

C Lei, J Liao, Q Li, J Shi, H Zhang, J Guo, Q Han… - Ecotoxicology and …, 2021 - Elsevier
Copper (Cu), one of the heavy metals, is far beyond the carrying capacity of the environment
with Cu mining, industrial wastewater discharging and the use of Cu-containing pesticides …

SS‐31 protects liver from ischemia‐reperfusion injury via modulating macrophage polarization

L Shang, H Ren, S Wang, H Liu, A Hu… - Oxidative medicine …, 2021 - Wiley Online Library
Ischemia‐reperfusion injury (IRI) is a common complication in liver surgeries. It is a focus to
discover effective treatments to reduce ischemia‐reperfusion injury. Previous studies show …

Emerging roles and therapeutic interventions of aerobic glycolysis in glioma

W Han, J Shi, J Cao, B Dong, W Guan - OncoTargets and therapy, 2020 - Taylor & Francis
Glioma is the most common type of intracranial malignant tumor, with a great recurrence rate
due to its infiltrative growth, treatment resistance, intra-and intertumoral genetic …

[HTML][HTML] Copper induces energy metabolic dysfunction and AMPK-mTOR pathway-mediated autophagy in kidney of broiler chickens

J Liao, F Yang, W Yu, N Qiao, H Zhang, Q Han… - Ecotoxicology and …, 2020 - Elsevier
To explore the effects of copper (Cu) on energy metabolism and AMPK-mTOR pathway-
mediated autophagy in kidney, a total of 240 one-day-old broiler chickens were randomized …