Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …

Lipid droplets (LDs) are ubiquitous organelles that play crucial roles in response to
physiological and environmental cues. The identification of several neutral lipid synthesizing …

Lipid droplets (LDs) and peroxisomes are ubiquitous organelles with central roles in
eukaryotic cells. Although the mechanisms involved in biogenesis of these organelles …

Peroxisomes are a dynamic compartment in almost all eukaryotic cells and have diverse
metabolic roles in response to environmental changes and cellular demands. The …

Saccharomyces cerevisiae contains three conserved reticulon and reticulon-like proteins
that help maintain ER structure by stabilizing high membrane curvature in ER tubules and …

In contrast to the molecular mechanisms underlying import of peroxisomal matrix proteins,
those involving the transport of membrane proteins remain rather elusive. At present, two …

The peroxisomal membrane protein (PMP) Pex3 and its cytosolic interaction partner Pex19
have been implicated in peroxisomal membrane biogenesis. Although these peroxins have …

Significant progress has been made towards our understanding of the mechanism of
peroxisome formation, in particular concerning sorting of peroxisomal membrane proteins …

Peroxisomes are unique organelles whose physiological functions vary depending on the
cellular environment or metabolic and developmental state of the organism. These changes …

Yarrowia lipolytica Pex23p and Saccharomyces cerevisiae Pex30p, Pex31p, and Pex32p
comprise a family of dysferlin domain–containing peroxins. We show that the deletion of …