The metabolic syndrome

MA Cornier, D Dabelea, TL Hernandez… - Endocrine …, 2008 - academic.oup.com
Abstract The “metabolic syndrome”(MetS) is a clustering of components that reflect
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the …

[HTML][HTML] High fat diet induces brain insulin resistance and cognitive impairment in mice

V Kothari, Y Luo, T Tornabene, AM O'Neill… - … et Biophysica Acta (BBA …, 2017 - Elsevier
High fat diet-induced obesity is associated with insulin resistance (IR) and other chronic, diet
related illnesses, including dementia. Alzheimer disease is the most common form of …

A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL/6 mice fed a high fat diet

JC Fraulob, R Ogg-Diamantino… - Journal of clinical …, 2010 - jstage.jst.go.jp
抄録 Diet-induced obesity in C57BL/6 mice triggers common features of human metabolic
syndrome (MetS). The purpose is to assess the suitability of a diet-induced obesity model for …

[PDF][PDF] High‐fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic …

R Kohli, M Kirby, SA Xanthakos, S Softic… - …, 2010 - Wiley Online Library
Diets high in saturated fat and fructose have been implicated in the development of obesity
and nonalcoholic steatohepatitis (NASH) in humans. We hypothesized that mice exposed to …

Pathophysiological mechanisms and clinical associations of non-alcoholic fatty pancreas disease

A Pagkali, A Makris, K Brofidi, AP Agouridis… - Diabetes, Metabolic …, 2024 - Taylor & Francis
Abstract Non-Alcoholic Fatty Pancreas disease (NAFPD), characterized by fat accumulation
in pancreatic tissue, is an emerging clinical entity. However, the clinical associations, the …

Adipose tissue dysfunction and visceral fat are associated with hepatic insulin resistance and severity of NASH even in lean individuals

C Saponaro, S Sabatini, M Gaggini, F Carli… - Liver …, 2022 - Wiley Online Library
Abstract Background & Aims Non‐alcoholic fatty liver disease (NAFLD) is a heterogeneous
disorder, but the factors that determine this heterogeneity remain poorly understood …

Gluten-free diet reduces adiposity, inflammation and insulin resistance associated with the induction of PPAR-alpha and PPAR-gamma expression

FLP Soares, R de Oliveira Matoso, LG Teixeira… - the Journal of nutritional …, 2013 - Elsevier
Gluten exclusion (protein complex present in many cereals) has been proposed as an
option for the prevention of diseases other than coeliac disease. However, the effects of …

High-fructose diet in pregnancy leads to fetal programming of hypertension, insulin resistance, and obesity in adult offspring

AF Saad, J Dickerson, TB Kechichian, H Yin… - American Journal of …, 2016 - Elsevier
Background Consumption of fructose-rich diets in the United States is on the rise and
thought to be associated with obesity and cardiometabolic diseases. Objective We sought to …

Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring

BM Gregorio, V Souza-Mello, JJ Carvalho… - American journal of …, 2010 - Elsevier
OBJECTIVE: This work aimed to verify the hypothesis that maternal intake of high-fat diet in
critical periods of pregnancy and/or suckling period predisposes nonalcoholic fatty liver …

The combination of high-fat diet-induced obesity and chronic ulcerative colitis reciprocally exacerbates adipose tissue and colon inflammation

LG Teixeira, AJ Leonel, EC Aguilar, NV Batista… - Lipids in health and …, 2011 - Springer
Background This study evaluated the relationship between ulcerative colitis and obesity,
which are both chronic diseases characterized by inflammation and increases in immune …