Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

Heme oxygenase 1 (HO-1) up-regulation is recognized as a pivotal mechanism of cell
adaptation to stress. Under control of different transcription factors but with a prominent role …

Abstract Heme-oxygenase 1 (HO-1) is an inducible enzyme known for its anti-inflammatory,
antioxidant and neuroprotective effects. However, increased expression of HO-1 during …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates
hundreds of antioxidant genes, and is activated in response to oxidative stress. Given that …

The heme oxygenase (HO) system is believed to be a crucial mechanism for the nervous
system under stress conditions. HO degrades heme to carbon monoxide, iron, and …

Strong adherence to a Mediterranean diet is associated with improved cognitive function
and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources …

Movement disorders are neurological conditions characterized by involuntary motor
movements, such as dystonia, ataxia, chorea myoclonus, tremors, Huntington's disease …

Nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) is a basic‐region leucine zipper
transcription factor that regulates the expression of many Phase II detoxifying/antioxidant …

Background Drug resistance is a particular problem in patients with temporal lobe epilepsy,
where seizures originate mainly from the hippocampus. Many of these epilepsies are …

Apoptosis of DA neurons is a contributing cause of disability and death for Parkinson's
disease (PD). In this experiment, the neuroprotective effect of Tricetin was examined in PD …