Malignant pleural mesothelioma (MPM) is an incurable cancer with a dismal prognosis and
few effective treatment options. Nonetheless, recent positive phase III trial results for immune …

Malignant pleural mesothelioma (MPM) is a clinical emergency of our time. Being strongly
associated with asbestos exposure, incidence of this cancer is ramping up these days in …

The exact mechanism of desmoplastic stromal reaction (DSR) formation is still unclear. The
interaction between cancer cells and cancer-associated fibroblasts (CAFs) has an important …

Malignant pleural mesothelioma is a rare and aggressive neoplasm, which has primarily
been attributed to the exposure to asbestos fibers (83% of cases); yet, despite a ban of using …

This paper summarizes recent insights into causal biological mechanisms underlying the
carcinogenicity of asbestos. It addresses their implications for the shapes of exposure …

Simple Summary Solitary fibrous tumor of the pleura (SFT) is an orphan disease resistant to
standard systemic therapy. We managed to establish two patient-derived cell models …

Simple Summary Asbestos exposure is known as the main elicitor of pleural mesothelioma
(PM) development. The pathology's rarity, wide range of growth patterns, and devastating …

Malignant pleural mesothelioma (MPM) is a rare but invasive cancer, which mainly arises
from mesothelial tissues of pleura, peritoneum and pericardium. Despite significant …

Objective Mesothelioma varies in clinical phenotype and survival. Clinical trials are
unavoidably affected by selection bias, reducing generalisability. ASSESS-meso is a UK …

Introduction Malignant pleural mesothelioma (MPM) is associated with poor prognosis and
is strongly associated with occupational asbestos exposure. Given the importance of …