Exosomes as a new frontier of cancer liquid biopsy
D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
A DNA-based hydrogel for exosome separation and biomedical applications
J Tang, X Jia, Q Li, Z Cui, A Liang… - Proceedings of the …, 2023 - National Acad Sciences
Exosomes (EXOs) have been proven as biomarkers for disease diagnosis and agents for
therapeutics. Great challenge remains in the separation of EXOs with high-purity and low …
therapeutics. Great challenge remains in the separation of EXOs with high-purity and low …
Molecular characterization of exosomes for subtype-based diagnosis of breast cancer
Y Cao, X Yu, T Zeng, Z Fu, Y Zhao, B Nie… - Journal of the …, 2022 - ACS Publications
Breast cancer is very heterogeneous and the most frequently diagnosed cancer worldwide,
and precise therapy targeting specific subtypes may improve the survival rates of breast …
and precise therapy targeting specific subtypes may improve the survival rates of breast …
Machine learning-based label-free SERS profiling of exosomes for accurate fuzzy diagnosis of cancer and dynamic monitoring of drug therapeutic processes
X Diao, X Li, S Hou, H Li, G Qi, Y Jin - Analytical Chemistry, 2023 - ACS Publications
Exosomes are a class of extracellular vesicles secreted by cells, which can be used as
promising noninvasive biomarkers for the early diagnosis and treatment of diseases …
promising noninvasive biomarkers for the early diagnosis and treatment of diseases …
Engineering a second‐order DNA logic‐gated nanorobot to sense and release on live cell membranes for multiplexed diagnosis and synergistic therapy
Tumor biomarker‐based theranostics have achieved broad interest and success in recent
years. However, single biomarker‐based recognition can cause false‐positive feedback …
years. However, single biomarker‐based recognition can cause false‐positive feedback …
One‐Step Thermophoretic AND Gate Operation on Extracellular Vesicles Improves Diagnosis of Prostate Cancer
J Deng, S Zhao, J Li, Y Cheng, C Liu… - Angewandte Chemie …, 2022 - Wiley Online Library
Circulating extracellular vesicles (EVs) have emerged as a valuable source of cancer
biomarkers. However, the high degree of EV heterogeneity and the complexity of clinical …
biomarkers. However, the high degree of EV heterogeneity and the complexity of clinical …
Dual-aptamer-assisted ratiometric SERS biosensor for ultrasensitive and precise identification of breast cancer exosomes
Q Zhang, R Ma, Y Zhang, J Zhao, Y Wang, Z Xu - ACS sensors, 2023 - ACS Publications
Due to the heterogeneity of breast cancer, its early accurate diagnosis remains a challenge.
Exosomes carry abundant genetic materials and proteins and are ideal biomarkers for early …
Exosomes carry abundant genetic materials and proteins and are ideal biomarkers for early …
Activating a DNA nanomachine via computation across cancer cell membranes for precise therapy of solid tumors
Y Zhang, W Chen, Y Fang, X Zhang… - Journal of the American …, 2021 - ACS Publications
Taking advantage of cancer cells' endogenous characters, the responsive activation of DNA
nanomachines has achieved great success in tumor therapy. Combining with extra stimuli …
nanomachines has achieved great success in tumor therapy. Combining with extra stimuli …
Functional DNA sensors integrated with nucleic acid signal amplification strategies for non-nucleic acid targets detection
Y Zhu, J Wu, Q Zhou - Biosensors and Bioelectronics, 2023 - Elsevier
In addition to carrying and transmitting genetic material, some DNA molecules have specific
binding ability or catalytic function. DNA with this special function is collectively referred to as …
binding ability or catalytic function. DNA with this special function is collectively referred to as …