Single vesicle molecular profiling has the potential to transform cancer detection and
monitoring by precisely probing cancer-associated extracellular vesicles (EVs) in the …

The advent of DNA nanotechnology has paved the way for the development of nanoscale
robotics capable of executing smart and sophisticated tasks in a programmed and automatic …

Sensitive and specific analysis of extracellular vesicles (EVs) offers a promising minimally
invasive way to identify malignant pulmonary nodules from benign lesions. However …

Aptamers are single-stranded DNA or RNA molecules that have high affinity and selectivity
to bind to specific targets. Compared to antibodies, aptamers are easy to in vitro synthesize …

Breast cancer is the most common malignant tumor in women, its incidence is secret, and
more than half of the patients are diagnosed in the middle and advanced stages, so it is …

Exosomes are seen as promising biomarkers for minimally invasive liquid biopsies and
disease surveillance. However, the complexity of body fluids, inherent heterogeneity, and …

Exosomal glycoproteins play significant roles in many physiological and pathological
procedures. However, the current methods for studying exosomal glycoproteins have low …

Circulating extracellular vesicles (EVs) are promising biomarkers for the early diagnosis and
prognosis of cancer in a non-invasive manner. However, the rapid and accurate …

Slow intermolecular collisions and “always active” responses compromise the amplification
efficiency and response accuracy of nonenzymatic hybridization chain reaction (HCR). In …

Exosome analysis is emerging as an attractive noninvasive approach for disease diagnosis
and treatment monitoring in the field of liquid biopsy. Aptamer is considered as a promising …