For more than two decades, the view that tumour-associated matrix metalloproteinases
(MMPs) were required for peritumour tissue degradation and metastasis dominated the drive …

Matrix metalloproteinases (MMPs) form a family of enzymes that mediate multiple functions
both in the tissue destruction and immune responses related to periodontal inflammation …

Extracellular proteolysis is an absolute requirement for new blood vessel formation
(angiogenesis). This review examines the role of the matrix metalloproteinase (MMP) and …

The matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases involved
in the degradation of the extracellular matrix. The MMPs have been implicated in the …

Degradation of extracellular matrix is crucial for malignant tumour growth, invasion,
metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc …

Migratory cells including invasive tumor cells frequently express CD44, a major receptor for
hyaluronan and membrane-type 1 matrix metalloproteinase (MT1-MMP) that degrades …

Various proteases are involved in cancer progression and metastasis. In particular,
gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9, have been implicated to play …

Following liver injury, hepatic stellate cells (HSCs) become activated and express a
combination of matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) …

Matrix metalloproteinases (MMP) play a role in a wide range of tumorigenesis, including
early carcinogenesis events, tumor growth and tumor invasion and metastasis. Given that …

Wound repair is initiated with the aggregation of platelets, formation of a fibrin clot, and
release of growth factors from the activated coagulation pathways, injured cells, platelets …