Chronic granulomatous disease (CGD) is an immunodeficiency disorder affecting about 1 in
250,000 individuals. The disease is caused by a lack of superoxide production by the …

Primary immunodeficiency diseases (PIDs) are a group of inherited disorders, characterized
by defects of the immune system predisposing individuals to variety of manifestations …

Infection of humans with M ycobacterium tuberculosis remains frequent and may still lead to
death. After primary infection, the immune system is often able to control M. tuberculosis …

Background The number of inherited diseases and the spectrum of clinical manifestations of
primary immunodeficiency disorders (PIDs) are ever-expanding. Molecular diagnosis using …

Recurrent severe bacterial and fungal infections are characteristic features of the rare
genetic immunodeficiency disorder chronic granulomatous disease (CGD). The disease …

Inflammatory bowel disease (IBD) is the consequence of an aberrant hemostasis of the
immune cells at the gut mucosal border. Based on clinical manifestation, laboratory tests …

Pediatric immunology came into sight in the second half of 20 th century, when pediatricians
and basic immunologists began to give attention to diagnosis and treatment of children with …

Primary immunodeficiency diseases (PID) comprise a heterogeneous group of inherited
diseases with a wide spectrum of clinical manifestations and laboratory abnormalities …

Introduction Chronic granulomatous disease (CGD) is a rare inherited condition resulting
from mutations in the genes that encode the proteins of the NADPH oxidase enzyme in …

Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by defect
in one of the components of nicotinamide adenine dinucleotide phosphate (NADPH) …