A poor diet, resulting in malnutrition, is a critical challenge that leads to a variety of metabolic
disorders, including obesity, diabetes, and cardiovascular diseases. Mentha species are …

Pulmonary arterial hypertension (PAH) is clinically characterized by a progressive increase
in pulmonary artery pressure, followed by right ventricular hypertrophy and subsequently …

Pulmonary hypertension (PH) is a progressive, pulmonary vascular disease with high
morbidity and mortality. Unfortunately, the pathogenesis of PH is complex and remains …

The endothelium, as the guardian of vascular homeostasis, is closely related to the
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …

In the current scenario, cardiovascular disease (CVD) is one of the most life-threatening
diseases that has caused high mortality worldwide. Several scientists, researchers, and …

Pulmonary arterial hypertension (PAH) is characterized by pulmonary artery remodeling that
may subsequently culminate in right heart failure and premature death. Although there are …

Pulmonary hypertension (PH) is a chronic and fatal disease, for which new therapeutic
drugs and approaches are needed urgently. Baicalein and baicalin, the active compounds …

Lamiaceae (Labiatae) are an important group of medicinal plants, which have been used for
treating heart disease in traditional medicine for centuries. These mainly aromatic plants are …

Although we have reported that baicalein ameliorated bleomycin-induced pulmonary
fibrosis in rats and inhibited fibroblast-to-myofibroblast differentiation, the mechanisms of the …

Pyrrolizidine alkaloids (PAs) are common phytotoxins with both hepatotoxicity and
pneumotoxicity. Hepatic cytochrome P450 enzymes are known to bioactivate PAs into …