Alzheimer's disease (AD) and Parkinson's disease (PD) are devastating, frequent, and still
incurable neurodegenerative diseases that manifest as cognitive and motor disorders …

Despite the availability of thrombolytic and endovascular therapy for acute ischemic stroke,
many patients are ineligible due to delayed hospital arrival. The identification of factors …

Background and Purpose—Previous work that predated the availability of the safer stent-
retriever devices has suggested that general anesthesia (GA) may have a negative impact …

Importance Given the limited time window available for treatment with tissue plasminogen
activator (tPA) in patients with acute ischemic stroke, guidelines recommend door-to …

Objective: Telestroke systems are tools, used to provide an advanced stroke care in regions
without sufficient neurologic services. We performed this meta-analysis to assess the effects …

Therapeutic effect of recombinant tissue-plasminogen activator (rt-PA) is time dependent.
There is limited evidence whether localization of stroke within the posterior circulation (PCS) …

Abstract Background Acute Ischemic Stroke (AIS) treatment has been revolutionised in the
last two decades with the increasing use of Intravenous Thrombolysis (IVT) and with the …

Introduction Knowledge of the implementation gap would facilitate the use of intravenous
thrombolysis in stroke, which is still low in many countries. The study was conducted to …

Background Thrombolysis using intravenous (IV) tissue plasminogen activator (tPA) is one
of few evidence-based acute stroke treatments, yet achieving high rates of IV tPA delivery …

Background Ischemic stroke is a time-sensitive disease, with improved outcomes associated
with decreased time from onset to treatment. It was hypothesised that ambulance-based …