[HTML][HTML] Anti-inflammatory and immunoregulatory effects of icariin and icaritin

Z Bi, W Zhang, X Yan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Inflammation and immunity dysregulation have received widespread attention in recent
years due to their occurrence in the pathophysiology of many conditions. In this regard …

[HTML][HTML] Icariin: A promising natural product in biomedicine and tissue engineering

Z Seyedi, MS Amiri, V Mohammadzadeh… - Journal of Functional …, 2023 - mdpi.com
Among scaffolds used in tissue engineering, natural biomaterials such as plant-based
materials show a crucial role in cellular function due to their biocompatibility and chemical …

[HTML][HTML] Advanced injectable hydrogels for cartilage tissue engineering

S Zhu, Y Li, Z He, L Ji, W Zhang, Y Tong… - … in bioengineering and …, 2022 - frontiersin.org
The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

[HTML][HTML] Engineering hyaluronic acid for the development of new treatment strategies for osteoarthritis

YS Kim, F Guilak - International journal of molecular sciences, 2022 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of
the joints, degradation of cartilage, and the remodeling of other joint tissues. Due to the …

Injectable hydrogels as promising in situ therapeutic platform for cartilage tissue engineering

R Cai, Y Shan, F Du, Z Miao, L Zhu, L Hang… - International Journal of …, 2024 - Elsevier
Injectable hydrogels are gaining prominence as a biocompatible, minimally invasive, and
adaptable platform for cartilage tissue engineering. Commencing with their synthesis, this …

[HTML][HTML] Gallic acid-grafted chitosan antibacterial hydrogel incorporated with polydopamine-modified hydroxyapatite for enhancing bone healing

Y Pang, L Guan, Y Zhu, R Niu, S Zhu… - … in Bioengineering and …, 2023 - frontiersin.org
An open critical-size bone defect is a major medical problem because of the difficulty in self-
healing, leading to an increased risk of bacterial infection owing to wound exposure …

[HTML][HTML] Icariin treatment rescues diabetes induced bone loss via scavenging ROS and activating primary cilia/Gli2/osteocalcin signaling pathway

J Liu, Q Cheng, X Wu, H Zhu, X Deng, M Wang, S Yang… - Cells, 2022 - mdpi.com
Diabetes-associated bone complications lead to fragile bone mechanical strength and
osteoporosis, aggravating the disease burden of patients. Advanced evidence shows that …

Novel strategies for the treatment of osteoarthritis based on biomaterials and critical molecular signaling

X Huang, Z Wang, H Wang, D Chen, L Tong - Journal of Materials Science …, 2023 - Elsevier
Osteoarthritis (OA) is a degenerative disease involving entire joint. It is often initiated from
the low-grade inflammation in synovial tissue and then affects articular cartilage and …

[HTML][HTML] Mesenchymal stromal cells laden in hydrogels for osteoarthritis cartilage regeneration: A systematic review from in vitro studies to clinical applications

C Manferdini, E Gabusi, Y Saleh, E Lenzi, G D'Atri… - Cells, 2022 - mdpi.com
This systematic review is focused on the main characteristics of the hydrogels used for
embedding the mesenchymal stromal cells (MSCs) in in vitro/ex vivo studies, in vivo OA …

[HTML][HTML] Effects of genus Epimedium in the treatment of osteoarthritis and relevant signaling pathways

X Tong, Y Wang, B Dong, Y Li, S Lang, J Ma, X Ma - Chinese Medicine, 2023 - Springer
Osteoarthritis (OA) is a common chronic degenerative joint disease in clinical practice with a
high prevalence, especially in the elderly. Traditional Chinese Medicine (TCM) believes that …