Early detection of cancer

D Crosby, S Bhatia, KM Brindle, LM Coussens, C Dive… - Science, 2022 - science.org
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer—2020 update. Part 1: screening, diagnosis, and local treatment with curative intent

N Mottet, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

[HTML][HTML] Prostate cancer screening with PSA and MRI followed by targeted biopsy only

J Hugosson, M Månsson, J Wallström… - … England Journal of …, 2022 - Mass Medical Soc
Background Screening for prostate cancer is burdened by a high rate of overdiagnosis. The
most appropriate algorithm for population-based screening is unknown. Methods We invited …

Genetics and biology of prostate cancer

G Wang, D Zhao, DJ Spring… - Genes & …, 2018 - genesdev.cshlp.org
Despite the high long-term survival in localized prostate cancer, metastatic prostate cancer
remains largely incurable even after intensive multimodal therapy. The lethality of advanced …

Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis

D Ilic, M Djulbegovic, JH Jung, EC Hwang, Q Zhou… - bmj, 2018 - bmj.com
Objective To investigate the efficacy and safety of prostate-specific antigen (PSA) testing to
screen for prostate cancer. Design Systematic review and meta-analysis. Data sources …

The fraction of cancer attributable to modifiable risk factors in England, Wales, Scotland, Northern Ireland, and the United Kingdom in 2015

KF Brown, H Rumgay, C Dunlop, M Ryan… - British journal of …, 2018 - nature.com
Background Changing population-level exposure to modifiable risk factors is a key driver of
changing cancer incidence. Understanding these changes is therefore vital when prioritising …

Prostate MRI, with or without MRI‐targeted biopsy, and systematic biopsy for detecting prostate cancer

FJH Drost, DF Osses, D Nieboer… - Cochrane Database …, 2019 - cochranelibrary.com
Background Multiparametric magnetic resonance imaging (MRI), with or without MRI‐
targeted biopsy, is an alternative test to systematic transrectal ultrasonography‐guided …

Digital rectal examination for prostate cancer screening in primary care: a systematic review and meta-analysis

L Naji, H Randhawa, Z Sohani, B Dennis… - The Annals of Family …, 2018 - Annals Family Med
PURPOSE Although the digital rectal examination (DRE) is commonly performed to screen
for prostate cancer, there is limited data to support its use in primary care. This review and …

[HTML][HTML] Prostate imaging-reporting and data system steering committee: PI-RADS v2 status update and future directions

AR Padhani, J Weinreb, AB Rosenkrantz, G Villeirs… - European urology, 2019 - Elsevier
Abstract Context The Prostate Imaging-Reporting and Data System (PI-RADS) v2 analysis
system for multiparametric magnetic resonance imaging (mpMRI) detection of prostate …

Prevention and early detection of prostate cancer

J Cuzick, MA Thorat, G Andriole, OW Brawley… - The lancet …, 2014 - thelancet.com
Prostate cancer is a common malignancy in men and the worldwide burden of this disease
is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control …