Oral Janus kinase inhibitors for atopic dermatitis
D Mikhaylov, B Ungar, Y Renert-Yuval… - Annals of Allergy …, 2023 - Elsevier
Atopic dermatitis (AD) is one of the most common inflammatory skin conditions. The
pathogenesis of AD involves skin barrier disruption and immune activation of T-helper (TH) …
pathogenesis of AD involves skin barrier disruption and immune activation of T-helper (TH) …
The socioeconomics of atopic dermatitis
J Chung, EL Simpson - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Objective To review the current state of the literature regarding the socioeconomics of atopic
dermatitis (AD)—more specifically how socioeconomic status (SES) affects AD risk and how …
dermatitis (AD)—more specifically how socioeconomic status (SES) affects AD risk and how …
Major adverse cardiovascular events in patients with atopic dermatitis treated with oral Janus kinase inhibitors: a systematic review and meta-analysis
C Ertus, LM Scailteux, A Lescoat… - British Journal of …, 2023 - academic.oup.com
Background On the basis of safety data for patients with inflammatory rheumatism or
inflammatory bowel disease, treatment with Janus kinase (JAK) inhibitors (JAKi) has been …
inflammatory bowel disease, treatment with Janus kinase (JAK) inhibitors (JAKi) has been …
Effectiveness and safety of upadacitinib in the treatment of moderate-severe atopic dermatitis: a multicentric, prospective, real-world, cohort study
A Chiricozzi, N Gori, A Narcisi, A Balato… - Drugs in R&D, 2022 - Springer
Background The efficacy and safety of upadacitinib in atopic dermatitis (AD) have been
defined in clinical trials, but no real-world data are currently available. We aimed to assess …
defined in clinical trials, but no real-world data are currently available. We aimed to assess …
Biological therapies for atopic dermatitis: An update
Severe atopic dermatitis, which affects both adults and children, is a debilitating disorder
with a significant decline of patients' quality of life. Although aetiopathogenic factors are …
with a significant decline of patients' quality of life. Although aetiopathogenic factors are …
Spesolimab, an anti‐interleukin‐36 receptor antibody, in patients with moderate‐to‐severe atopic dermatitis: Results from a multicentre, randomized, double‐blind …
R Bissonnette, W Abramovits… - Journal of the …, 2023 - Wiley Online Library
Background Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease, and
there is increasing evidence that the interleukin (IL)‐36 pathway may play a role in the …
there is increasing evidence that the interleukin (IL)‐36 pathway may play a role in the …
Janus kinase inhibitors for atopic dermatitis: a promising treatment modality
AM Cartron, TH Nguyen, YS Roh… - Clinical and …, 2021 - academic.oup.com
Atopic dermatitis (AD) is chronic, pruritic, inflammatory skin disease that affects a significant
portion of the population in industrialized nations. For nonresponders to conventional …
portion of the population in industrialized nations. For nonresponders to conventional …
Atopic dermatitis in adults
JI Silverberg - Medical Clinics, 2020 - medical.theclinics.com
Atopic dermatitis (AD) was once thought to be primarily a pediatric disease that remitted with
increasing age. However, recent epidemiologic studies showed that AD is a common and …
increasing age. However, recent epidemiologic studies showed that AD is a common and …
[HTML][HTML] A systematic review and meta-analysis of risk factors associated with atopic dermatitis in Asia
YT Ng, FT Chew - World Allergy Organization Journal, 2020 - Elsevier
Background Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterised by
intense itch and eczematous lesions. Rising prevalence of AD has been observed …
intense itch and eczematous lesions. Rising prevalence of AD has been observed …
Interleukin-4 as a therapeutic target
Abstract Interleukin-4 (IL-4) is a pleiotropic cytokine mainly known for its role in type 2
immunity. Therapies antagonizing or blocking IL-4 activity have been developed to …
immunity. Therapies antagonizing or blocking IL-4 activity have been developed to …