Cholinesterase inhibition activity and docking simulation study of coumarin mannich base derivatives
Inhibition of acetylcholinesterase and butyrylcholinesterase (AChE and BuChE) as two
major forms of cholinesterases (ChEs) is considered as the common approach for the …
major forms of cholinesterases (ChEs) is considered as the common approach for the …
[PDF][PDF] The effects and mechanisms of the action of galangin on spatial memory in rats
The effects and mechanisms of the action of galangin on spatial memory in rats Page 1
Indexed and abstracted in Science Citation Index Expanded and in Journal Citation Reports/Science …
Indexed and abstracted in Science Citation Index Expanded and in Journal Citation Reports/Science …
Inhibitory activity on cholinesterases produced by aryl-phthalimide derivatives: green synthesis, in silico and in vitro evaluation
O Ruiz-Maciel, II Padilla-Martínez… - Medicinal Chemistry …, 2020 - Springer
Background Alzheimer's disease (AD) is characterized by cognitive impairment and loss of
immediate memory resulting from neuronal death in different brain areas, mainly those …
immediate memory resulting from neuronal death in different brain areas, mainly those …
Synthesis, Docking and Acetylcholinesterase Inhibitory Evaluation of 1, 3, 4-Thiadiazole Derivatives as Potential Anti-Alzheimer Agents
A Mohammadi-Farani, M Takesh… - Pharmaceutical …, 2024 - ps.tbzmed.ac.ir
Background: According to the cholinergic hypothesis for Alzheimer's disease, potentiation of
cholinergic neurotransmission is one of the best strategies for combating dementia …
cholinergic neurotransmission is one of the best strategies for combating dementia …
Investigation into anti-Alzheimer activity of newly developed phthalimide derivatives in experimental animals
The present study was designed to investigate anti-Alzheimer's activity and to quantify brain
neurotransmitter of newly developed isoindoline-1, 3-dione derivatives (IDDs). The anti …
neurotransmitter of newly developed isoindoline-1, 3-dione derivatives (IDDs). The anti …
[HTML][HTML] Novel acetylcholinesterase inhibitors: Synthesis, docking and inhibitory activity evaluation of 4-benzamido-N-(1-benzylpiperidin-4-yl) benzamide derivatives
A Mohammadi-Farani, S Nazari, M Mohammadi… - Results in …, 2024 - Elsevier
The cholinergic hypothesis is one of the basic approaches for designing and discovering
novel anti-Alzheimer drugs. Application of the pharmacophore of well-known drugs like …
novel anti-Alzheimer drugs. Application of the pharmacophore of well-known drugs like …
[HTML][HTML] Cytotoxicity and pro-apoptosis activity of synthetic 1, 3-thiazole incorporated phthalimide derivatives on cancer cells
O Tavallaei, M Heidarian, M Marzbany… - Iranian Journal of Basic …, 2021 - ncbi.nlm.nih.gov
Objective (s): Cancer is the second important reason for death worldwide. In spite of
advances in cancer treatment, however, survival of patients stays weak. Therefore, there is a …
advances in cancer treatment, however, survival of patients stays weak. Therefore, there is a …
Synthesis and acetylcholinesterase inhibitory assessment of benzamide derivatives incorporated piperazine moiety as potential anti-Alzheimer agents
A Aliabadi, A Mohammadi-Farani… - Journal of …, 2017 - search.proquest.com
According to the obtained information from X-ray crystallography, it has been characterized
that two distinct parts are observable in the active site of AChE.[...] the ethylacetate was …
that two distinct parts are observable in the active site of AChE.[...] the ethylacetate was …
Synthesis, docking and acetylcholinesterase inhibitory evaluation of (E)-3-(4-(diethylamino) phenyl)-1-phenylprop-2-en-1-one derivatives with probable anti …
A Aliabadi, A Mohammadi-Farani… - Journal of Reports in …, 2017 - journals.lww.com
Alzheimer's disease (AD) as form of senile dementia is a cognitive and neurodegenerative
disorder as well as behavioral and psychological problems in the geriatric people. The …
disorder as well as behavioral and psychological problems in the geriatric people. The …
[PDF][PDF] Coumarin derivatives as acetyl-and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics
MN Abu-Aisheh, A Al-Aboudi, MS Mustafa, M Mustafa… - academia.edu
Alzheimer's disease is an irreversible and progressive brain disease that can cause
problems with memory and thinking skills. It is characterized by loss of cognitive ability and …
problems with memory and thinking skills. It is characterized by loss of cognitive ability and …