Simple Summary Breast cancer is an ideal model of a heterogeneous disease that is
triggered by genetic changes in the normal mammary epithelial cells and manifest as …

Breast cancer is one of the leading causes contributing to the global cancer burden. The
triple negative breast cancer (TNBC) molecular subtype accounts for the most aggressive …

Background DNA methylation is a dynamic epigenetic mechanism that occurs at cytosine-
phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) …

Exosomes, nanometer-sized membranous vesicles in body fluids, have emerged as
promising non-invasive biomarkers for cancer diagnosis. However, the function of exosomes …

Breast cancer (BC), the most prevalent cancer in women, is a heterogenous disease.
Despite advancements in BC diagnosis, prognosis, and therapeutics, survival rates have …

The standard treatment of ovarian cancer (OC) patients, including debulking surgery and
first-line chemotherapy, is unsatisfactory because of recurrent episodes in the majority …

Introduction Cyclosporine (CsA), a potent immunosuppressive chemotherapeutic
medication, treats numerous cancers, particularly malignant carcinoma, acute leukemia, and …

Network biology finds application in interpreting molecular interaction networks and
providing insightful inferences using graph theoretical analysis of biological systems. The …

microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-
125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous …

Background Blood DNA methylation can inform us about the biological mechanisms that
underlie common disease states. Previous epigenome-wide analyses of common diseases …