In order to fully understand any complex biochemical system from a mechanistic point of
view, it is necessary to have access to the three-dimensional structures of the molecular …

How cells move is a fundamental biological question. The directionality of adherent
migrating cells depends on the assembly and disassembly (turnover) of focal adhesions …

Septins are cytoskeletal proteins that assemble into hetero-oligomeric complexes and sense
micron-scale membrane curvature. During infection with Shigella flexneri, an invasive …

Septins are cytoskeletal proteins conserved from algae and protists to mammals. A unique
feature of septins is their presence as heteromeric complexes that polymerize into filaments …

The cytoskeleton comprises three polymerizing structures that have been studied for a long
time, actin microfilaments, microtubules and intermediate filaments, plus more recently …

Long-range membrane traffic is guided by microtubule-associated proteins and
posttranslational modifications, which collectively comprise a traffic code. The regulatory …

Septins, a family of GTP-binding proteins that assemble into higher order structures,
interface with the membrane, actin filaments and microtubules, and are thus important …

Septins are cytoskeletal proteins interacting with the inner plasma membrane and other
cytoskeletal partners. Being key in membrane remodeling processes, they often localize at …

The microtubule cytoskeleton consists of microtubule subsets with distinct compositions of
microtubule-associated proteins, which instruct the position and traffic of subcellular …

For the population over 65, long-term care (LTC) expenditure constitutes a considerable
share in health care expenditures. In this paper, we decompose health care into medical …