Covering: 2000 to 2020 Triptolide is a bioactive diterpene triepoxide isolated from
Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant whose extracts have …

Covering: 1980s–2014 In this study, the biological properties of natural abietane-type
diterpenoids with an aromatic C ring are reviewed. An overview of the synthetic studies of …

Paclitaxel is a well known anticancer compound. Its biosynthesis involves the formation of a
highly functionalized diterpenoid core skeleton (baccatin III) and the subsequent assembly …

Tanshinones are the bioactive nor-diterpenoid constituents of the Chinese medicinal herb
Danshen (Salvia miltiorrhiza). These groups of chemicals have the characteristic furan D …

Carnosic acid (salvin), which possesses antioxidative and antimicrobial properties, is
increasingly exploited within the food, nutritional health and cosmetics industries. Since its …

Salvia miltiorrhiza Bunge (Danshen) is a medicinal plant of the Lamiaceae family, and its
dried roots have long been used in traditional Chinese medicine with hydrophilic phenolic …

Cytochrome P450 enzymes (CYPs) play major roles in generating highly functionalized
terpenoids, but identifying the exact biotransformation step (s) catalyzed by plant CYP in …

Salvia miltiorrhiza Bunge is an herb rich in bioactive tanshinone and salvianolic acid
compounds. It is primarily used as an effective medicine for treating cardiovascular and …

Triptolide is a trace natural product of Tripterygium wilfordii. It has antitumor activities,
particularly against pancreatic cancer cells. Identification of genes and elucidation of the …

Microbial production can be advantageous over the extraction of phytoterpenoids from
natural plant sources, but it remains challenging to rationally and rapidly access efficient …