Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors

DQ Huang, P Mathurin, H Cortez-Pinto… - Nature reviews …, 2023 - nature.com
Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, alcohol per-
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …

Alcohol-associated hepatitis

R Bataller, JP Arab, VH Shah - New England Journal of Medicine, 2022 - Mass Medical Soc
Alcohol-Associated Hepatitis | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Diagnosis and management of cirrhosis and its complications: a review

EB Tapper, ND Parikh - Jama, 2023 - jamanetwork.com
Importance Cirrhosis affects approximately 2.2 million adults in the US. From 2010 to 2021,
the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

[HTML][HTML] Alcohol consumption and metabolic syndrome: clinical and epidemiological impact on liver disease

F Åberg, CD Byrne, CJ Pirola, V Männistö… - Journal of …, 2023 - Elsevier
Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

Alcohol-associated liver disease

B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

The stigma of alcohol-related liver disease and its impact on healthcare

G Schomerus, A Leonhard, J Manthey, J Morris… - Journal of …, 2022 - Elsevier
People with alcohol-related liver disease (ALD) experience stigma and discrimination. This
review summarises the evidence on stigma in healthcare and its implications for people with …

Melatonin: A mitochondrial resident with a diverse skill set

RJ Reiter, R Sharma, S Rosales-Corral… - Life Sciences, 2022 - Elsevier
Melatonin is an ancient molecule that originated in bacteria. When these prokaryotes were
phagocytized by early eukaryotes, they eventually developed into mitochondria and …

Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

J Ma, A Guillot, Z Yang, B Mackowiak… - The Journal of …, 2022 - Am Soc Clin Investig
Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH)
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …