Hematopoietic stem cells (HSCs) are responsible for the lifelong production of all blood cells
[1]. Like many other tissues and organs, the hematopoietic system develops during …

The development of all humans begins after the union of male and female gametes or germ
cells during fertilization or conception. The fertilized egg or zygote is a large diploid cell that …

The ability to proliferate is a common feature of most T-cell populations. However,
proliferation follows different cell-cycle dynamics and is coupled to different functional …

This paper presents a sequence of steps oriented to gain biological knowledge from
microarray gene expression data. The pipeline's core is a canonical multi-objective Genetic …

Hematopoietic stem cells (HSCs) are stem cells from mesodermal derivation that reside in
bone marrow and provide blood cells for the whole life of an adult individual, through a …

Abstract Lissencephaly-1 (Lis1) protein is a dynein-binding protein involved in neural stem
cell division, morphogenesis and motility. To determine whether Lis1 is a key factor in …

How hematopoietic stem cells (HSCs) coordinate their divisional axis and whether this
orientation is important for stem cell–driven hematopoiesis is poorly understood. Single-cell …

皮质酮对体外培养发育中胎鼠脑皮层神经元迁移蛋白LIS1表达的影响- PMC Back to Top Skip to
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Cell fate regulation is a central component of maintaining tissue homeostasis, yet the
mechanisms instructing cell division diversity in tissue-specific stem cells have not been well …

Understanding the evolution of the cancer cell from a normal cell holds the key to
developing novel, potent therapies against cancer. Two hypotheses describing the origins of …