Bad guys turned nice? A critical assessment of Wolbachia mutualisms in arthropod hosts

R Zug, P Hammerstein - Biological Reviews, 2015 - Wiley Online Library
Wolbachia are the most abundant bacterial endosymbionts among arthropods. Although
maternally inherited, they do not conform to the widespread view that vertical transmission …

Wolbachia and the biological control of mosquito‐borne disease

I Iturbe‐Ormaetxe, T Walker, SL O'Neill - EMBO reports, 2011 - embopress.org
Mosquito‐borne diseases such as malaria, dengue fever and filariasis cause an enormous
health burden to people living in tropical and subtropical regions of the world. Despite years …

The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations

T Walker, PH Johnson, LA Moreira, I Iturbe-Ormaetxe… - Nature, 2011 - nature.com
Dengue fever is the most important mosquito-borne viral disease of humans with more than
50 million cases estimated annually in more than 100 countries,. Disturbingly, the …

Impact of Wolbachia on Infection with Chikungunya and Yellow Fever Viruses in the Mosquito Vector Aedes aegypti

AF Van Den Hurk, S Hall-Mendelin… - PLoS neglected …, 2012 - journals.plos.org
Incidence of disease due to dengue (DENV), chikungunya (CHIKV) and yellow fever (YFV)
viruses is increasing in many parts of the world. The viruses are primarily transmitted by …

Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia

FD Frentiu, T Zakir, T Walker, J Popovici… - PLoS neglected …, 2014 - journals.plos.org
Introduction Dengue is one of the most widespread mosquito-borne diseases in the world.
The causative agent, dengue virus (DENV), is primarily transmitted by the mosquito Aedes …

Harnessing mosquito–Wolbachia symbiosis for vector and disease control

K Bourtzis, SL Dobson, Z Xi, JL Rasgon, M Calvitti… - Acta tropica, 2014 - Elsevier
Mosquito species, members of the genera Aedes, Anopheles and Culex, are the major
vectors of human pathogens including protozoa (Plasmodium sp.), filariae and of a variety of …

Wolbachia Variants Induce Differential Protection to Viruses in Drosophila melanogaster: A Phenotypic and Phylogenomic Analysis

E Chrostek, MSP Marialva, SS Esteves… - PLoS …, 2013 - journals.plos.org
Wolbachia are intracellular bacterial symbionts that are able to protect various insect hosts
from viral infections. This tripartite interaction was initially described in Drosophila …

The Relative Importance of Innate Immune Priming in Wolbachia-Mediated Dengue Interference

E Rancès, YH Ye, M Woolfit, EA McGraw… - PLoS …, 2012 - journals.plos.org
The non-virulent Wolbachia strain w Mel and the life-shortening strain w MelPop-CLA, both
originally from Drosophila melanogaster, have been stably introduced into the mosquito …

Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains

J Martinez, B Longdon, S Bauer, YS Chan… - PLoS …, 2014 - journals.plos.org
In the last decade, bacterial symbionts have been shown to play an important role in
protecting hosts against pathogens. Wolbachia, a widespread symbiont in arthropods, can …

Wolbachia Induces Density-Dependent Inhibition to Dengue Virus in Mosquito Cells

P Lu, G Bian, X Pan, Z Xi - PLoS neglected tropical diseases, 2012 - journals.plos.org
Wolbachia is a maternal transmitted endosymbiotic bacterium that is estimated to infect up to
65% of insect species. The ability of Wolbachia to both induce viral interference and spread …