Ligand recognition by αβ T cell receptors
MM Davis, JJ Boniface, Z Reich, D Lyons… - Annual review of …, 1998 - annualreviews.org
▪ Abstract While still incomplete, the first data concerning the biochemistry of T cell receptor–
ligand interactions in cell-free systems seem to have considerable predictive value …
ligand interactions in cell-free systems seem to have considerable predictive value …
Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules
P Schuck - Annual review of biophysics and biomolecular …, 1997 - annualreviews.org
▪ Abstract Surface plasmon resonance biosensors have become increasingly popular for the
qualitative and quantitative characterization of the specific binding of a mobile reactant to a …
qualitative and quantitative characterization of the specific binding of a mobile reactant to a …
T-cell-receptor affinity and thymocyte positive selection
SM Alam, PJ Travers, JL Wung, W Nasholds… - Nature, 1996 - nature.com
Abstract DEVELOPMENT of thymocytes involves two distinct outcomes resulting from
superficially similar events. Recognition by thymocytes of major histocompatibility complex …
superficially similar events. Recognition by thymocytes of major histocompatibility complex …
Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors
DG Myszka - Current opinion in biotechnology, 1997 - Elsevier
Surface plasmon resonance based biosensors are being used to define the kinetics of a
wide variety of macromolecular interactions. As the popularity of this approach grows …
wide variety of macromolecular interactions. As the popularity of this approach grows …
The structural basis of T cell activation by superantigens
▪ Abstract Superantigens (SAGs) are a class of immunostimulatory and disease-causing
proteins of bacterial or viral origin with the ability to activate large fractions (5–20%) of the T …
proteins of bacterial or viral origin with the ability to activate large fractions (5–20%) of the T …
Crystal structure of a T-cell receptor β-chain complexed with a superantigen
SUPERANTIGENS (SAgs) are viral or bacterial proteins that act as potent T-cell stimulants
and have been implicated in a number of human diseases, including toxic shock …
and have been implicated in a number of human diseases, including toxic shock …
A Shannon entropy analysis of immunoglobulin and T cell receptor
JJ Stewart, CY Lee, S Ibrahim, P Watts… - Molecular …, 1997 - Elsevier
In 1970, before any antigen-bound immunoglobulin structure had been solved, Elvin Kabat
proposed that regions of high amino acid diversity would be the antigen binding sites of …
proposed that regions of high amino acid diversity would be the antigen binding sites of …
[HTML][HTML] Three-dimensional structure of the complex between a T cell receptor β chain and the superantigen staphylococcal enterotoxin B
Superantigens (SAGs) are a class of immunostimulatory proteins of bacterial or viral origin
that activate T cells by binding to the Vβ domain of the T cell antigen receptor (TCR). The …
that activate T cells by binding to the Vβ domain of the T cell antigen receptor (TCR). The …
Paroxetine attenuates cardiac hypertrophy via blocking GRK2 and ADRB1 interaction in hypertension
X Sun, M Zhou, G Wen, Y Huang, J Wu… - Journal of the …, 2021 - Am Heart Assoc
Background ADRB1 (adrenergic receptor beta 1) responds to neuroendocrine stimulations,
which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) …
which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) …
Global analysis of community‐associated methicillin‐resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection
C Burlak, CH Hammer, MA Robinson… - Cellular …, 2007 - Wiley Online Library
Community‐associated methicillin‐resistant Staphylococcus aureus (CA‐MRSA) is a threat
to human health worldwide. Although progress has been made, mechanisms of CA‐MRSA …
to human health worldwide. Although progress has been made, mechanisms of CA‐MRSA …