Allergic diseases are caused by a hypersensitivity reaction to an external substance that is
normally not harmful to the body. An imbalance between type 2 immune response and …

Current management of severe asthma relying either on guidelines (bulk approach) or on
disease phenotypes (stratified approach) did not improve the burden of the disease. Several …

Asthma is an inflammatory disease of the lung airway network, which is initiated and
perpetuated by allergen-specific CD4+ T cells, IgE antibodies, and a massive release of Th2 …

The number of patients with allergic asthma is rising yearly, and hormonal drugs, such as
dexamethasone, have unique advantages and certain limitations. In the treatment of allergic …

Biallelic inactivating mutations in IL21R causes a combined immunodeficiency that is often
complicated by cryptosporidium infections. While eight IL-21R-deficient patients have been …

Adiponectin is an adipokine associated with the healthy obese phenotype. Adiponectin
increases insulin sensitivity and has cardio and vascular protection actions. Studies related …

Tuo-Min-Ding-Chuan decoction (TMDCT) is a Traditional Chinese Medicine (TCM) formula
consisting of twelve herbs that can relieve the symptoms and treat allergic asthma. Yet, the …

Ethnopharmacological relevance Asthma is a costly global health problem that negatively
influences the quality of life of patients. The Chinese Materia Medica (CMM) contains …

Parasitic diseases cause significant morbidity and mortality in the developing and
underdeveloped countries. No efficacious vaccines are available against most parasitic …

Background Inflammatory patterns in chronic rhinosinusitis (CRS) may predict disease
severity, need for multiple sinus surgeries, and treatment response. This study analyzes …