High-fiber plant foods contain lignans that are converted to bioactive enterolignans,
enterolactone (ENL) and enterodiol (END) by gut bacteria. Previously, we conducted an …

Abstract Background: Cardiovascular diseases (CVDs) are the leading cause of death
globally, making their prevention a major challenge for modern society. For decades …

Abstract Purpose of Review Precision nutrition requires a solid understanding of the factors
that determine individual responses to dietary treatment. We review the current state of …

Advances in high-throughput DNA sequencing have propelled research into the human
microbiome and its link to metabolic health. We explore microbiome analysis methods …

Nutritional intake impacts the human epigenome by directing epigenetic pathways in normal
cell development via as yet unknown molecular mechanisms. Consequently, imbalance in …

Gene–nutrient interactions (GeNuIne) collaboration, a large-scale collaborative project, has
been initiated to investigate the impact of gene–nutrient interactions on cardiometabolic …

Objectives Using a nationally-representative, cross-sectional cohort, we examined
nutritional markers of undiagnosed type 2 diabetes in adults via machine learning. Methods …

Lipids and lipoproteins are major targets for cardiovascular disease (CVD) prevention.
Findings from a limited number of clinical trials suggest diet-induced atherogenic lipoprotein …

Objective Identifying predictors of weight loss and clinical outcomes may increase
understanding of individual variability in weight loss response. We hypothesized that …

The impact of polyphenols in ovarian cancer is widely studied observing gene expression,
epigenetic alterations, and molecular mechanisms based on new 'omics' technologies …