[HTML][HTML] Damage-mediated macrophage polarization in sterile inflammation

G Koncz, V Jenei, M Tóth, E Váradi, B Kardos… - Frontiers in …, 2023 - frontiersin.org
Most of the leading causes of death, such as cardiovascular diseases, cancer, dementia,
neurodegenerative diseases, and many more, are associated with sterile inflammation …

Electrospun fiber-based strategies for controlling early innate immune cell responses: towards immunomodulatory mesh designs that facilitate robust tissue repair

D Venugopal, S Vishwakarma, I Kaur, S Samavedi - Acta Biomaterialia, 2023 - Elsevier
Electrospun fibrous meshes are widely used for tissue repair due to their ability to guide a
host of cell responses including phenotypic differentiation and tissue maturation. A critical …

[HTML][HTML] Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases

M Karaky, G Boucher, S Mola, S Foisy… - PLoS …, 2022 - journals.plos.org
Background Genome wide association studies (GWAS) have identified and validated more
than 200 genomic loci associated with the inflammatory bowel disease (IBD), although for …

Qing-Luo-Yin alleviated experimental arthritis in rats by disrupting immune feedback between inflammatory T cells and monocytes: key evidences from its effects on …

DD Wang, XY Wu, JY Dong, XP Cheng… - Journal of …, 2021 - Taylor & Francis
Background Qing-Luo-Yin (QLY) is an anti-rheumatic herbal formula. Despite the well-
investigated therapeutic efficacy of QLY, its immune regulatory properties are largely …

[HTML][HTML] Reduced monocyte proportions and responsiveness in convalescent COVID-19 patients

EV Ravkov, ESCP Williams, M Elgort… - Frontiers in …, 2024 - frontiersin.org
Introduction The clinical manifestations of acute severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) …

[HTML][HTML] A micro-immunotherapy sequential medicine MIM-seq displays immunomodulatory effects on human macrophages and anti-tumor properties towards in vitro …

C Jacques, I Marchesi, FP Fiorentino… - International Journal of …, 2022 - mdpi.com
In this study, the immunomodulatory effects of a sequential micro-immunotherapy medicine,
referred as MIM-seq, were appraised in human primary M1 and M2 macrophages, in which …

[HTML][HTML] Photon-and Proton-Mediated Biological Effects: What Has Been Learned?

E Jumaniyazova, D Smyk, P Vishnyakova… - Life, 2022 - mdpi.com
The current understanding of the effects of radiation is gradually becoming broader.
However, it still remains unclear why some patients respond to radiation with a pronounced …

Chemotherapy, hypothyroidism and oral dysbiosis as a novel risk factor of cardiovascular pathology development

A Avagimyan, T Gvianishvili, L Gogiashvili… - Current Problems in …, 2023 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in the
population, as well as the economic burden of the health care system. Currently, CVDs …

[HTML][HTML] Distinct gene expression patterns for CD14++ and CD16++ monocytes in preeclampsia

P Vishnyakova, M Kuznetsova, A Poltavets… - Scientific Reports, 2022 - nature.com
Preeclampsia (PE) is a serious gestational complication affecting the life of a mother and
child. The immunophenotype and gene expression profile of isolated blood monocyte …

Direct assessment of leukocyte signalling and cytokine secretion reveals exercise intensity‐dependent reductions in anti‐inflammatory cytokine action

H Islam, SH Tsai, C Figueiredo… - The Journal of …, 2024 - Wiley Online Library
Abstract Circulating interleukin (IL)‐6 and IL‐10 concentrations are widely used to evaluate
the anti‐inflammatory effects of exercise but do not capture cytokine action at the cellular …