Immunotherapy has transformed treatment for various types of malignancy. However, the
benefit of immunotherapy is limited to a minority of patients with mismatch-repair-deficient …

Simple Summary In this review, we present current knowledge about the prognostic and
predictive role of tumor-infiltrating lymphocytes (TILs) in ovarian cancer since this tumor …

The subtypes of duodenal cancer (DC) are complicated and the carcinogenesis process is
not well characterized. We present comprehensive characterization of 438 samples from …

Background As the most common gastrointestinal malignancy worldwide, liver metastases
occur in half colorectal cancer (CRC) patients. Early detection can help treat them early and …

Germline BRCA1/2 alterations in the Homologous Recombination (HR) pathway are
considered as main susceptibility biomarkers to Hereditary Breast and Ovarian Cancers …

Ovarian cancer, one of the deadliest malignancies, lacks effective treatment, despite
advancements in surgical techniques and chemotherapy. Thus, new therapeutic …

The most common subtype of ovarian cancer (OC) is the high-grade serous ovarian
carcinoma (HGSOC), accounting for 70%–80% of all OC deaths. Although HGSOC is a …

Background Colorectal cancers with defects in the Mismatch Repair (MMR) system
represent a minority of the disease. MMR defective cancers are characterized by high Tumor …

Hereditary breast and ovarian cancer syndrome is caused by germline mutations in
BRCA1/2 genes. These genes are very large and their mutations are heterogeneous and …

Abstract Background Small bowel adenocarcinomas (SBAs) are rare and there is little
comprehensive data on SBA genomic alterations for Asian patients. This study aimed to …